The efficacy of N-2-butyl cyanoacrylate in the fixation of nasal septum to the anterior nasal spine in rabbits

Basit Öğe Kaydı
dc.authorid0000-0003-2619-0829
dc.contributor.authorAlkan, Seyhan
dc.contributor.authorDadaş, Burhan
dc.contributor.authorÇelik, Deniz
dc.contributor.authorCoşkun, Berna Uslu
dc.contributor.authorYılmaz, Fahrettin
dc.contributor.authorBaşak, Tülay
dc.date.accessioned2024-09-25T19:59:58Z
dc.date.available2024-09-25T19:59:58Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü en_US
dc.description.abstractIn nasal septal surgery, fixing the caudal portion of the nasal septum to the anterior nasal spine is difficult with the present techniques. N-2-butyl cyanoacrylate is a form of cyanoacrylate which is bioabsorbable and biocompatible. The feasibility and efficacy of the compound, which is easy to apply to the tissues, for the above purpose is investigated in this experimental study. Fourteen New Zealand rabbits were included in the study. The nasal septum was exposed with the open approach (transcolumellar). In the study group (n = 10), the septum was detached from the nasal floor and attached to a point 3 mm lateral to the nasal spine on the right side, using 2-butyl cyanoacrylate. In control group (n = 4) it was deviated 3 mm to the right side and left for spontaneous healing without using any fixation method. Beginning on the third postoperative week, one animal was sacrificed under general anesthesia, every week in the study group and every third week in the control group, and the septum was analysed. Foreign body reaction, histotoxicity, and the structure of the regenerative tissue in the junction of bone and cartilage were analysed with histopathology. The success of stabilization in the study group, where the septum was attached with N-2-butyl cyanoacrylate, was significantly superior to the control group where no fixation method was used (P < 0.05). Histopathologically, there were no differences between the two groups with respect to foreign body reaction, histotoxicity, and the tissue that formed between the bone and cartilage (P > 0.05). This study demonstrated that N-2-Butyl cyanoacrylate was successful in the fixation of the caudal edge of the nasal septum to the anterior nasal spine. No serious infections, foreign body reaction, necrosis or histotoxicity were observed.en_US
dc.identifier.doi10.1007/s00405-007-0407-9
dc.identifier.endpage1430en_US
dc.identifier.issn0937-4477
dc.identifier.issue12en_US
dc.identifier.pmid17676330en_US
dc.identifier.startpage1425en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-007-0407-9
dc.identifier.urihttps://hdl.handle.net/20.500.12491/14010
dc.identifier.volume264en_US
dc.identifier.wosWOS:000250442100008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYılmaz, Fahrettin
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectSeptal Surgeryen_US
dc.subjectN-2-Butyl Cyanoacrylateen_US
dc.subjectExperimentalen_US
dc.subjectNasal Septum
dc.subjectHistotoxicity
dc.subjectHistopathologically
dc.titleThe efficacy of N-2-butyl cyanoacrylate in the fixation of nasal septum to the anterior nasal spine in rabbitsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
seyhan-alkan.pdf
Boyut:
310.72 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/Full text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Cerrahi Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu