Evaluation of subjects with a moderate cup to disc ratio using optical coherence tomography and Heidelberg retina tomograph 3: impact of the disc area

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dc.authorid0000-0003-4468-3985
dc.authorid0000-0002-8249-2621
dc.authorid0000-0003-1018-925X
dc.authorid0000-0001-8305-6600
dc.contributor.authorUlaş, Fatih
dc.contributor.authorDoğan, Ümit
dc.contributor.authorKaymaz, Abdulgani
dc.contributor.authorÇelik, Fatih
dc.contributor.authorÇelebi, Serdal
dc.date.accessioned2021-06-23T19:42:34Z
dc.date.available2021-06-23T19:42:34Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim was to evaluate subjects with a moderate cup to disc ratio using optical coherence tomograph (OCT) and Heidelberg retina tomograph (HRT) 3. Settings and Design: We included 80 patients with early glaucoma and 80 nonglaucomatous subjects with moderate cup/disc ratio (range of 0.5-0.8) to this cross-sectional study. Subjects and Methods: We compared results of color-coded algorithms of HRT 3 (Moorfields regression analysis [MRA] and Glaucoma probability score [GPS]) and OCT. All outputs are classified into three categories: Within normal limits (WNLs), borderline and outside normal limits (ONLs). Diagnostic accuracies of algorithms were determined using the highest sensitivity criteria. Results: The sensitivities of global MRA, GPS and OCT were 0.75, 0.925 and 0.725, respectively, in average disc area group and 0.85, 1.0 and 0.425, respectively, in large disc area group. The specificities of global MRA, GPS and OCT were 0.55, 0.15 and 0.85, respectively, in average disc area group and 0.425, 0.025 and 0.80, respectively, in large disc area group. Area under receiver operating characteristic curve (AUROC) of global MRA, GPS and OCT were 0.667, 0.617 and 0.792, respectively, in average disc area group and 0.746, 0.576 and 0.627, respectively, in large disc area group. AUROC of global MRA and OCT combination in the average and large disc area groups were 0.828 and 0.825, respectively. Conclusions: In contrast to GPS and OCT algorithms, diagnostic performance of MRA algorithm increased in large disc area group. Combining MRA and OCT algorithms produced satisfactory diagnostic performance in subjects with an average and large disc area.en_US
dc.identifier.doi10.4103/0301-4738.151454
dc.identifier.endpage8en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.issue1en_US
dc.identifier.pmid25686054en_US
dc.identifier.scopus2-s2.0-84923414025en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3en_US
dc.identifier.urihttps://doi.org/10.4103/0301-4738.151454
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8538
dc.identifier.volume63en_US
dc.identifier.wosWOS:000350110500002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.institutionauthorDoğan, Ümit
dc.institutionauthorKaymaz, Abdulgani
dc.institutionauthorÇelik, Fatih
dc.institutionauthorÇelebi, Serdal
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofIndian Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCup to Disc Ratioen_US
dc.subjectDisc Areaen_US
dc.subjectglaucoma probability scoreen_US
dc.subjectMoorfields Regression Analysisen_US
dc.subjectOptical Coherence Tomographyen_US
dc.titleEvaluation of subjects with a moderate cup to disc ratio using optical coherence tomography and Heidelberg retina tomograph 3: impact of the disc areaen_US
dc.typeArticleen_US

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