Dermatofibrosarcoma protuberans: A rare malignancy

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dc.authorid0000-0002-6839-2632
dc.authorid0000-0001-6768-1275
dc.authorid0000-0001-5588-0306
dc.authorid0000-0001-7965-6229
dc.contributor.authorÜyetürk, Ümmügül
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorDüzcü, Selma Erdoğan
dc.contributor.authorKüçüköztaş, Nadire
dc.contributor.authorYılmaz, Fahri
dc.date.accessioned2021-06-23T18:41:24Z
dc.date.available2021-06-23T18:41:24Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor characterized by protuberant growth pattern of skin and subcutaneous tissue. The annual incidence is 4.2 per million. It is often seen between the ages of 20–50 years. This study aimed to evaluate the characteristics of patients with DFSP. METHODS Patients who visited our clinic were retrospectively evaluated. RESULTS All patients were females and the median age was 42 (29–60) years. The evaluated tumor sites were observed in the body/trunk in one patient, at the hip in two, and at the proximal lower extremity in two. Sur gical excision was done in all of them as initial treatment. Re-excision was needed in three patients. One of the patients underwent punch biopsy for diagnosis and surgical removal of the tumor with a negative surgical margin. One of the patients underwent radiotherapy. The median follow-up time was 10 (6–26) months. During the median follow-up, there was no local recurrence or metastasis. CONCLUSION As initial treatment, it is important to surgically remove tumors that had no distant metastasis. Positive or near surgical margins should be resected again. If a negative surgical margin cannot be achieved, radiotherapy should be used as the treatment. Imatinib mesylate is used for treatment in unresectable, recurrent, and/or metastatic tumors.en_US
dc.identifier.endpage152en_US
dc.identifier.issn1300-7467
dc.identifier.issn2717-8978
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85038355602en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage148en_US
dc.identifier.trdizinid270498en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpjd05EazRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3389
dc.identifier.volume32en_US
dc.identifier.wosWOS:000424788200003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÜyetürk, Ümmügül
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorDüzcü, Selma Erdoğan
dc.institutionauthorKüçüköztaş, Nadire
dc.institutionauthorYılmaz, Fahri
dc.language.isoenen_US
dc.relation.ispartofTürk Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDermatofibrosarcoma Protuberansen_US
dc.subjectİmatinib
dc.subjectRadiotherapy
dc.subjectSurgery
dc.titleDermatofibrosarcoma protuberans: A rare malignancyen_US
dc.typeArticleen_US

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