Effects of isoflurane on postoperative olfactory memory

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dc.authorid0000-0002-1630-2033en_US
dc.authorid0000-0003-4139-5080
dc.authorid0000-0002-4229-6589
dc.authorid0000-0002-2311-6431
dc.contributor.authorBilgi, Murat
dc.contributor.authorDemirhan, Abdullah
dc.contributor.authorAkkaya, Akcan
dc.contributor.authorTekelioğlu, Ümit Yaşar
dc.contributor.authorErdem, Kemalettin
dc.contributor.authorApuhan, Tayfun
dc.contributor.authorKurt, Adem
dc.date.accessioned2021-06-23T19:36:49Z
dc.date.available2021-06-23T19:36:49Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: In this study, we planned to investigate the effects of isoflurane 1.2%, on olfactory memory. Methods: This is a prospective clinical study conducted over 40 patients aged 18-50 who had elective surgery and American Society of Anesthesiologists (ASA) physical status I-II. The Brief Smell Identification Test (BSIT) was used for interpreting patients' olfactory memories before and after the surgical procedure. Patients received standard general anesthesia protocol and routine monitoring. For induction, 1.5 mg/kg of fentanyl, 2 mg/kg of propofol, and 0.5 mg/kg of rocuronium bromide were administered. Anesthesia was maintained with the inhalational of anesthetic isofluraine (1.2%). The scores are recorded 30 minute before the surgery and when the Aldrate Recovery Score reached 10 in the postoperative period. Preoperative and postoperative results were compared and p-values <0.05 were considered statistically significant. Results: The patients' mean age were 38.4 +/- 13.8. Preoperative total correct answer rate to odorous substances was 91.4%, and postoperative rate was 90.8%. Percentage of the odor substance identification by the patients revealed no statistically significant difference when pre and post-operative rates have been compared. (P>0.05) Conclusion: In conclusion, it is the first time we demonstrate general anesthesia with isoflurane 1.2 % has no significant effect on the olfactory memory. Further studies with larger samples will be required to confirm our findings.en_US
dc.identifier.endpage456en_US
dc.identifier.issn0393-6384
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84898409116en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage453en_US
dc.identifier.urihttps://www.actamedicamediterranea.com/archive/2014/medica-2/effects-of-isoflurane-on-postoperative-olfactory-memory/document
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8061
dc.identifier.volume30en_US
dc.identifier.wosWOS:000335937900026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBilgi, Murat
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorAkkaya, Akcan
dc.institutionauthorTekelioğlu, Ümit Yaşar
dc.institutionauthorErdem, Kemalettin
dc.institutionauthorApuhan, Tayfun
dc.institutionauthorKurt, Adem
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectisoflurane 1.2%en_US
dc.subjectOlfactory Memoryen_US
dc.titleEffects of isoflurane on postoperative olfactory memoryen_US
dc.typeArticleen_US

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