Effects of isoflurane on postoperative olfactory memory
Yükleniyor...
Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Carbone Editore
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: In this study, we planned to investigate the effects of isoflurane 1.2%, on olfactory memory. Methods: This is a prospective clinical study conducted over 40 patients aged 18-50 who had elective surgery and American Society of Anesthesiologists (ASA) physical status I-II. The Brief Smell Identification Test (BSIT) was used for interpreting patients' olfactory memories before and after the surgical procedure. Patients received standard general anesthesia protocol and routine monitoring. For induction, 1.5 mg/kg of fentanyl, 2 mg/kg of propofol, and 0.5 mg/kg of rocuronium bromide were administered. Anesthesia was maintained with the inhalational of anesthetic isofluraine (1.2%). The scores are recorded 30 minute before the surgery and when the Aldrate Recovery Score reached 10 in the postoperative period. Preoperative and postoperative results were compared and p-values <0.05 were considered statistically significant. Results: The patients' mean age were 38.4 +/- 13.8. Preoperative total correct answer rate to odorous substances was 91.4%, and postoperative rate was 90.8%. Percentage of the odor substance identification by the patients revealed no statistically significant difference when pre and post-operative rates have been compared. (P>0.05) Conclusion: In conclusion, it is the first time we demonstrate general anesthesia with isoflurane 1.2 % has no significant effect on the olfactory memory. Further studies with larger samples will be required to confirm our findings.
Açıklama
Anahtar Kelimeler
isoflurane 1.2%, Olfactory Memory
Kaynak
Acta Medica Mediterranea
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
30
Sayı
2
