Effect of hemodialysis duration on conjunctival bacterial flora and susceptibility of conjunctival bacterial isolates to fluoroquinolones

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dc.authorid0000-0002-2915-4666en_US
dc.authorid0000-0003-4468-3985
dc.contributor.authorBalbaba, Mehmet
dc.contributor.authorUlaş, Fatih
dc.contributor.authorAltunışık, Sibel
dc.date.accessioned2021-06-23T19:34:32Z
dc.date.available2021-06-23T19:34:32Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: To determine the differences between conjunctival bacterial flora of hemodialysis patients and healthy subjects, the effect of duration of hemodialysis on conjunctival bacterial flora, and in vitro antibiotic susceptibility patterns of conjunctival bacterial flora to fluoroquinolones. Methods: Sixty healthy subjects (32 male, 28 female) and 60 hemodialysis patients (33 male, 27 female) who had renal failure due to reasons other than diabetic nephropathy and with no previous history of intraocular surgery participated in this study. Statistical analysis of the difference between the culture positivity of hemodialysis patients and a control group was determined using the chi-square test. Pearson's correlation test was used to quantify the correlations among culture positivity and duration of hemodialysis. Results: Conjunctival culture positivity of the hemodialysis patients and the control group was 58.3 and 45.0%, respectively, and there was no statistically significant difference between these groups (p = 0.144). Pearson's correlation test revealed that there was a weak but statistically significant positive correlation between culture positivity and duration of hemodialysis (r value was 0.378 [p = 0.003]). Staphylococcus aureus (28.3%) and Staphylococcus epidermidis (20.0%) were the most frequently isolated organisms in the hemodialysis patients, Staphylococcus epidermidis (26.7%) and Staphylococcus aureus (6.7%) were the most frequently isolated organisms in the control group. Resistance of most frequently isolated organisms (Staphylococcus aureus and Staphylococcus epidermidis) from control group and hemodialysis patients to ofloxacin, levofloxacin, moxifloxacin, and gatifloxacin were 20, 15, 5, and 5%, and 34.5, 20.7, 6.9, and 6.9%, respectively. Conclusions: As distinct from the control group, S. aureus colonization was isolated more from the hemodialysis patients. Culture positivity of the hemodialysis patients was positively correlated with the duration of hemodialysis. Antibiotic susceptibility of isolates from conjunctival bacterial flora of hemodialysis patients were less than healthy control group.en_US
dc.identifier.doi10.3109/09273948.2012.758747
dc.identifier.endpage200en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue3en_US
dc.identifier.pmid23514529en_US
dc.identifier.scopus2-s2.0-84878428489en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://doi.org/10.3109/09273948.2012.758747
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7544
dc.identifier.volume21en_US
dc.identifier.wosWOS:000319572200004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology And Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibiotic Susceptibilityen_US
dc.subjectConjunctival Floraen_US
dc.subjectFluoroquinoloneen_US
dc.subjectHemodialysisen_US
dc.subjectHemodialysis Durationen_US
dc.titleEffect of hemodialysis duration on conjunctival bacterial flora and susceptibility of conjunctival bacterial isolates to fluoroquinolonesen_US
dc.typeArticleen_US

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