Effect of patient weight and scanning duration on contrast enhancement during pulmonary multidetector CT angiography

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dc.authorid0000-0001-5428-0368
dc.contributor.authorBae, Kyongtae T.
dc.contributor.authorTao, Cheng
dc.contributor.authorGürel, Safiye
dc.contributor.authorHong, Cheng
dc.contributor.authorZhu, Fang
dc.contributor.authorGebke, Todd A.
dc.contributor.authorMilite, Margherita
dc.date.accessioned2021-06-23T19:20:33Z
dc.date.available2021-06-23T19:20:33Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: To retrospectively evaluate the amount of contrast medium required with 16- and 64-section computed tomography (CT) for a given patient weight to achieve desirable contrast enhancement during pulmonary CT angiography. Materials and Methods: Institutional review board approval was obtained, and informed consent was not required for this HIPAA-compliant study. Eighty-five patients (35 men, 50 women; range, 22 - 87 years) who had undergone 16- section (n = 48) or 64-section (n = 37) CT for the detection of pulmonary embolism were retrospectively evaluated. Contrast medium containing 350 mg of iodine per milliliter was injected at a rate of 4 mL/sec. The injected volume corresponded to the injection rate multiplied by the sum of the scanning delay plus the scanning duration, up to 125 mL. The scanning delay was determined with bolus tracking. Contrast enhancement was measured in the main pulmonary artery and the aorta. For each patient, the injected contrast medium volume per body weight index was calculated. Linear regression analysis was performed, and the Wilcoxon signed rank test was used to assess differences between 16- and 64-section CT. Results: A range of patient weights (45.3-153.0 kg) and contrast medium volumes (76 - 125 mL) were noted. The regression formula indicated that 1.2 mL per kilogram body weight of contrast medium was required to achieve 250 HU. The median scanning duration was shorter for 64-section CT than for 16- section CT (5.7 seconds vs 9.5 seconds, P < .001).Consequently, 64-section CT required 17.6% less contrast medium than did 16- section CT (85.4 mL vs 103.6 mL, P < .001). Median contrast enhancement in the pulmonary artery was 8.9% lower with 64-section CT than with 16- section CT (257.7 HU vs 282.9 HU, P = .11). Conclusion: To achieve consistent contrast enhancement during pulmonary CT angiography, the amount of contrast medium can be adjusted to the patient's body weight.en_US
dc.identifier.doi10.1148/radiol.2422052132
dc.identifier.endpage589en_US
dc.identifier.issn0033-8419
dc.identifier.issue2en_US
dc.identifier.pmid17255426en_US
dc.identifier.scopus2-s2.0-33846420993en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage582en_US
dc.identifier.urihttps://doi.org/10.1148/radiol.2422052132
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6133
dc.identifier.volume242en_US
dc.identifier.wosWOS:000244032100032en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGürel, Safiye
dc.language.isoenen_US
dc.publisherRadiological Soc North Americaen_US
dc.relation.ispartofRadiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCT angiographyen_US
dc.titleEffect of patient weight and scanning duration on contrast enhancement during pulmonary multidetector CT angiographyen_US
dc.typeArticleen_US

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