Microwave-assisted synthesis and odor characteristics of some new isoxazolidines
Yükleniyor...
Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We describe herein the design and synthesis of new isoxazolidin-5-carboxylates by microwave-assisted 1,3-dipolar cycloadditions of aldonitrones, derived from five fragrant aldehydes, with methacrylate esters. The reaction proceeded regioselectively providing mostly endo- diastereomers and in some cases an inseparable mixture of endo-exo products. The structures of target compounds were identified on the basis of IR, NMR, and TOF-MS measurements. Besides, both aldonitrone and isoxazolidine derivatives were subjected to olfactory evaluation by an expert nose. Diverse fragrance notes were observed in each series of isoxazolidines bearing different groups from aldonitrones. However, their odor ranges were found as animalic, medical, waxy, and ozonic undertones in common.
Açıklama
TUBITAK (Turkish Scientific and Technological Research Council)(Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK))
Anahtar Kelimeler
Aldonitrone, Isoxazolidine, Methacrylate Ester, Microwave Heating, Odor, Inhibition
Kaynak
Synthetic Communications
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
52
Sayı
21
Künye
Sağırlı, A., Acar, H., Özçal, H. E., & Büyükbayram, M. (2022). Microwave-assisted synthesis and odor characteristics of some new isoxazolidines. Synthetic Communications, 52(21), 2067-2077.
