Relationship between erythrocyte catalase and serum adenosine deaminase activities in eclampsia

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dc.authorid0000-0002-5344-9739en_US
dc.authorid0000-0003-3804-7966en_US
dc.authorid0000-0002-4060-3354en_US
dc.contributor.authorKolusarı, Ali
dc.contributor.authorKurdoğlu, Mertihan
dc.contributor.authorBuğdaycı, Güler
dc.contributor.authorAdalı, Ertan
dc.contributor.authorYıldızhan, Recep
dc.contributor.authorÇebi, Ayşegül
dc.contributor.authorDemir, Halit
dc.date.accessioned2021-06-23T19:26:32Z
dc.date.available2021-06-23T19:26:32Z
dc.date.issued2009
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective. To examine the relationship between antioxidant status and T-cell activation in the pathogenesis of eclampsia by measuring the activities of erythrocyte catalase, an enzyme of antioxidant mechanism, and serum adenosine deaminase (ADA), regarded as a marker of T-cell activation. Methods. A total of 60 patients [20 eclamptic (E) pregnant women, 20 healthy pregnant (HP) women and 20 non-pregnant (NP) women] were included in the study. Maternal venous blood samples were obtained from each patient during weeks 28-37 of gestation, and biochemical analyses of catalase activity in erythrocytes and ADA activity in serum were carried out. Results. Erythrocyte catalase activity was significantly lower and serum ADA activity was significantly higher in the E pregnant women when compared with the HP women and NP women (P 0.001). No significant correlation was observed between erythrocyte catalase activity and serum ADA activity. Conclusions. Erythrocyte catalase and serum ADA activities may at least in part contribute to the pathogenesis of eclampsia. However, more studies are needed to verify and clarify the relationship between antioxidant status and T-cell activation in eclampsia.en_US
dc.identifier.doi10.1080/14767050802702356
dc.identifier.endpage324en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue4en_US
dc.identifier.pmid19172437en_US
dc.identifier.scopus2-s2.0-67651023985en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage321en_US
dc.identifier.urihttps://doi.org/10.1080/14767050802702356
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6579
dc.identifier.volume22en_US
dc.identifier.wosWOS:000265583100007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBuğdaycı, Güler
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEclampsiaen_US
dc.subjectErythrocyteen_US
dc.subjectCatalaseen_US
dc.subjectAdenosine Deaminaseen_US
dc.titleRelationship between erythrocyte catalase and serum adenosine deaminase activities in eclampsiaen_US
dc.typeArticleen_US

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