Cutaneous silent period in fibromyalgia

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dc.authorid0000-0002-1845-0902en_US
dc.authorid0000-0002-9647-4432
dc.contributor.authorŞahin, Özlem
dc.contributor.authorYıldız, Serpil
dc.contributor.authorYıldız, Nebil
dc.date.accessioned2021-06-23T19:28:09Z
dc.date.available2021-06-23T19:28:09Z
dc.date.issued2011
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: The pathogenesis of widespread pain and increased tenderness in Fibromyalgia (FM) are still unknown. Recently, the role of central nervous system hyperexcitability is emphasized in pathogenesis of FM. The central sensitization was demonstrated with decrease in nociceptive flexion reflex (NFR) threshold in patients with FM. The NFR and cutaneous silent period (CuSP) are excitatory and inhibitory parts of the same spinal protective reflex, respectively. The aim of this study was to evaluate the changes in CuSP in FM. Patients and methods: Twenty-eight patients with FM and 18 healthy volunteers were subjected to the study. CuSPs on right abductor pollicis brevis muscle evoked by electrical stimulation of the right fifth digit were recorded. Results: The CuSP onset latencies were significantly longer in patients with FM. There was not any significant difference in CuSP duration between patients and controls. Conclusion: The latency elongation of the CuSP shows that there is some delay in the development of the inhibitory part of the spinal protective reflex in patients with FM. The observed changes in CuSP of the patients with FM may suggest some abnormalities in the circuits of sensorimotor integration at spinal and supraspinal levels. The results regarding the changes observed in the CuSP in patients with FM should be confirmed by further studies.en_US
dc.identifier.doi10.1179/016164110X12767786356516
dc.identifier.endpage343en_US
dc.identifier.issn0161-6412
dc.identifier.issue4en_US
dc.identifier.pmid21535931en_US
dc.identifier.scopus2-s2.0-79955943896en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage339en_US
dc.identifier.urihttps://doi.org/10.1179/016164110X12767786356516
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6964
dc.identifier.volume33en_US
dc.identifier.wosWOS:000290093300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldız, Serpil
dc.institutionauthorYıldız, Nebil
dc.language.isoenen_US
dc.publisherManey Publishingen_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCutaneous Silent Perioden_US
dc.subjectCutaneous Stimulationen_US
dc.subjectFibromyalgiaen_US
dc.subjectProtective Reflexen_US
dc.subjectSpinal Inhibitory Reflexen_US
dc.titleCutaneous silent period in fibromyalgiaen_US
dc.typeArticleen_US

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