Diabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levels

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-3085-7964en_US
dc.authorid0000-0002-3836-2125en_US
dc.authorid0000-0003-4201-9757en_US
dc.contributor.authorErkuş, Edip
dc.contributor.authorAktaş, Gülali
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorAtak, Burçin Meryem
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:53:44Z
dc.date.available2021-06-23T19:53:44Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: Vitamin D deficiency is not only associated with bone metabolism but also with diabetes mellitus. We aimed to study the possible association between serum vitamin D concentration and HbA1c level in patients with type 2 diabetes mellitus (T2DM) in this retrospective report. METHODS: Patients with T2DM were enrolled to the study either in regulated or non-regulated T2DM groups, according to HbA1c levels. An HbA1c level of <8% was considered as relatively controlled and others were considered as poorly controlled T2DM. RESULTS: Serum vitamin D levels in poorly controlled T2DM subjects (9.4 (4.9-34) ng/ml) were significantly lower than that of the relatively well regulated T2DM patients (13.5 (3.4-36) ng/ml) (p=0.03). Vitamin D was strongly and inversely correlated with HbA1c levels (r= -0.295, p=0.005). CONCLUSION: Whatever the cause or result of the diabetes mellitus, it is clear that lower vitamin D is strongly associated with worse diabetic regulation in T2DM subjects. Randomized controlled larger studies, which research the relation between diabetic regulation and vitamin D status, are needed to claim whether it could be a therapeutic target in future in diabetic subjects.en_US
dc.identifier.doi10.1590/1806-9282.65.1.51
dc.identifier.endpage55en_US
dc.identifier.issn1806-9282
dc.identifier.issue1en_US
dc.identifier.pmid30758420en_US
dc.identifier.scopus2-s2.0-85061482666en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage51en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.65.1.51
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10215
dc.identifier.volume65en_US
dc.identifier.wosWOS:000458029400009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVitamin Den_US
dc.subjectType 2 Diabetes Mellitusen_US
dc.subjectGlycated Hemoglobin Aen_US
dc.titleDiabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levelsen_US
dc.typeArticleen_US

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