Descemet's membrane area and posterior corneal power may predict the Descemet membrane folds after deep anterior lamellar keratoplasty in patients with advanced keratoconus

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dc.authorid0000-0001-9111-8060en_US
dc.authorid0000-0001-9945-793Xen_US
dc.authorid0000-0002-7804-6055en_US
dc.authorid0000-0002-7031-3729en_US
dc.authorid0000-0001-8511-7504en_US
dc.contributor.authorÖzgür, Armağan
dc.contributor.authorÜçgül, Ahmet Yücel
dc.contributor.authorÇubuk, Mehmet Özgür
dc.contributor.authorOnat, Emrah
dc.contributor.authorCeylanoğlu, Kübra Serbest
dc.contributor.authorAydın, Bahri
dc.date.accessioned2023-07-21T11:48:25Z
dc.date.available2023-07-21T11:48:25Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAims To investigate possible predictive topographic characteristics for the development of Descemet's membrane (DM) folds after the uneventful deep anterior lamellar keratoplasty (DALK). Methods A retrospective study included 56 eyes of 56 consecutive patients who underwent uneventful DALK using the big-bubble technique to treat advanced keratoconus. At baseline and each visit, best-corrected logMAR visual acuity (BCVA), slit-lamp findings, endothelial cell density, topographic parameters were recorded. DM area is calculated using morphogeometric modelling. Results Twelve (21.4%) of them exhibited DM folds, whereas the remaining 44 (78.6%) did not exhibit any DM folds after the surgery. The mean follow-up time was 36.3 +/- 16.7 (range, 12-71) months. The mean posterior corneal power was - 13.8 +/- 0.6 D in patients with DM folds, whereas - 13.0 +/- 0.8 D in those without DM folds (p = 0.016). The mean DM area was 53.6 +/- 2.3 (50.9-57.9) mm(2) in patients with DM folds, whereas 51.6 +/- 1.7 (47.1-53.9) mm(2) in those without DM folds (p = 0.001). The ROC curve showed that two best cut-off value for the posterior corneal power and DM area were 13.75 D and 53.8 mm(2), respectively, to predict the occurrence of DM folds. Conclusion DALK surgery seems to cause DM folds in patients with large DM area and high posterior corneal power.en_US
dc.identifier.citationOzgur, A., Ucgul, A. Y., Cubuk, M. O., Onat, E., Ceylanoglu, K. S., Aydın, B., & Yuksel, E. (2021). Descemet’s membrane area and posterior corneal power may predict the Descemet membrane folds after deep anterior lamellar keratoplasty in patients with advanced keratoconus. International Ophthalmology, 41(12), 4017-4024.en_US
dc.identifier.doi10.1007/s10792-021-01974-z
dc.identifier.endpage4024en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue12en_US
dc.identifier.pmid34296350en_US
dc.identifier.scopus2-s2.0-85110988512en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4017en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s10792-021-01974-z
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11330
dc.identifier.volume41en_US
dc.identifier.wosWOS:000675789900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÜçgül, Ahmet Yücel
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdvanced Keratoconusen_US
dc.subjectDeep Anterior Lamellar Keratoplastyen_US
dc.subjectDescemet's Membrane Areaen_US
dc.subjectDescemet's Membrane Foldsen_US
dc.subjectPosterior Corneal Poweren_US
dc.subjectDALKen_US
dc.titleDescemet's membrane area and posterior corneal power may predict the Descemet membrane folds after deep anterior lamellar keratoplasty in patients with advanced keratoconusen_US
dc.typeArticleen_US

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