Time interval between E and E' waves can predict complicated clinical course in patients with acute pulmonary embolism

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dc.authorid0000-0001-6595-7493en_US
dc.authorid0000-0002-4380-7045en_US
dc.authorid0000-0003-1784-3584en_US
dc.contributor.authorAcar, Emrah
dc.contributor.authorKılıçgedik, Alev
dc.contributor.authorİzci, Servet
dc.contributor.authorİnanir, Mehmet
dc.contributor.authorYılmaz, Mehmet Fatih
dc.contributor.authorGökçe, Mustafa
dc.date.accessioned2023-06-24T15:03:19Z
dc.date.available2023-06-24T15:03:19Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose Acute pulmonary embolism is a life-threatening cardiothoracic emergency leading to right ventricle systolic and diastolic dysfunction. In the present study, we investigated the right ventricle diastolic function and its predictive value in patients with acute pulmonary embolism. Material and methods Were prospectively recruited in this study 621 patients diagnosed with acute pulmonary embolism between December 2015 and June 2019. Among them, 173 were excluded, leaving 448 patients for follow-up. Transthoracic echocardiography was performed for the evaluation of the right ventricle systolic and diastolic indices. At 30-day follow-up, the patients were allocated either into the benign or in the complicated clinical course group. Results The group with complicated clinical course had higher value of pulmonary artery systolic pressure (PASP), right/left ventricle diameter ratio, E-wave velocity, E/A ratio, A ' wave velocity, E/E ' ratio, and time interval between E and E ' waves (P < .05), but lower values of tricuspid annular plane systolic excursion, A-wave velocity, isovolumetric relaxation time, deceleration time, E ', and E '/A ' (P < .05). Complicated clinical course was associated with shorter isovolumetric relaxation time (r = .564, P < .001), E/E ' (r = .495, P < .001), and TE-E ' (r = .596, P < .001). Receiver operator characteristic curve analysis showed that TE-E ' had the largest area under curve (TE-E ' 0.82, IVRT 0.77, E/E ' 0.72). A cut-off value of TE-E ' = 70 milliseconds had an 81.1% sensitivity and 71.4% specificity for the prediction of the complicated clinical course. Conclusion The assessment of the right ventricle diastolic function could predict the complicated clinical course in patients with acute pulmonary embolism.en_US
dc.identifier.citationAcar, E., Kilicgedik, A., Izci, S., Inanir, M., Yilmaz, M. F., Gokce, M., ... & Kirma, C. (2021). Time interval between E and E′ waves can predict complicated clinical course in patients with acute pulmonary embolism. Journal of Clinical Ultrasound, 49(6), 580-585.en_US
dc.identifier.doi10.1002/jcu.22995
dc.identifier.endpage585en_US
dc.identifier.issn0091-2751
dc.identifier.issn1097-0096
dc.identifier.issue6en_US
dc.identifier.pmid33660282en_US
dc.identifier.scopus2-s2.0-85101936415en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage580en_US
dc.identifier.urihttp://dx.doi.org/10.1002/jcu.22995
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11204
dc.identifier.volume49en_US
dc.identifier.wosWOS:000625079400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorİnanir, Mehmet
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Ultrasounden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiastole Dysfunctionen_US
dc.subjectEchocardiographyen_US
dc.subjectPulmonary Arteryen_US
dc.subjectPulmonary Embolismen_US
dc.subjectRight Ventricleen_US
dc.titleTime interval between E and E' waves can predict complicated clinical course in patients with acute pulmonary embolismen_US
dc.typeArticleen_US

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