Yazar "Gözdaş, Hasan Tahsin" seçeneğine göre listele
Listeleniyor 1 - 20 / 28
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Adult-onset subacute sclerosing panencephalitis presented with neuropsychiatric symptoms(NLM (Medline), 2019) Gökoglu, Abdülkerim; Gözdaş, Hasan TahsinSubacute sclerosing panencephalitis (SSPE) is a progressive neurodegenerative disease caused by persistent infection of the brain with the measles virus. The most clinical presentations are behavioural changes and deterioration of mental status. The diagnosis is made with the characteristic clinical picture along with the consistent laboratory findings such as increased anti-measles antibody levels in cerebrospinal fluid accompanied by typical electroencephalographic and cranial imaging findings. SSPE usually affects children. Adult-onset SSPE is very rare and often presents with atypical features. We report here the case of a 62-year female presented with neuropsychiatric symptoms in whom SSPE was diagnosed based on cerebrospinal fluid, electroencephalographic and cranial imaging findings.Öğe Are we aware of q fever enough? Experience from a single centre(2019) Gözdaş, Hasan Tahsin; Sırmatel, Fatma; Karabörk, Şeyma; Akdeniz, HayrettinABSTRACT BACKGROUND: Q fever is a zoonosis caused by Coxiella burnetii. The main clinical presentations are pneumonia and hepatitis. However, it can be difficult to recognise Q fever due to many different clinical presentations. In this study, we aimed to increase the awareness of Q fever by presenting clinical and laboratory features of Q fever cases from our institution. MATERIAL and METHODS: Patients with a diagnosis of Q fever in our hospital database were evaluated retrospectively. Patient characteristics as well as clinical and laboratory values at presentation were recorded. RESULTS: A total of six patients were included in this study. Various clinical presentation was observed such as fever, anorexia and malaise as the most common symptoms. The most common laboratory abnormality was CRP elevation as being detected in all patients followed by LDH and transaminase elevations. both were found in four patients. CONCLUSION: Serological methods used to diagnose Q fever are not routinely performed, so Q fever cases can be missed easily. We believe that Q fever should be investigated further in patients from endemic regions who did not give adequate response to nonspesific antibiotic treatment.Öğe Brucellar epididymo-orchitis: a retrospective study of 25 cases(Taylor & Francis Ltd, 2020) Gözdaş, Hasan Tahsin; Bal, TayibeObjective: Brucellosis is a multisystemic disease which may affect all organs. Epididymo-orchitis is the most common form of genitourinary involvement. The aim of this study was to present our eight-year experience regarding the management of patients with brucellar epididymo-orchitis (BEO). Materials and method: The medical records of male brucellosis patients treated in two centers, between 2010 and 2018 were analyzed retrospectively. The diagnosis of epididymo-orchitis was made when the patients had scrotal pain, swelling, and enlarged tender testicles and/or epididymis on clinical examination. Brucellosis was diagnosed with a positive standard tube agglutination test or a positive blood culture. Results: Brucellosis was diagnosed in 996 male patients. Of these patients, 25 had a diagnosis of BEO (2.5%). All BEO patients suffered from enlarged painful testicles, however, testicular complaints were the only presentation symptoms in three of them. All patients received medical treatment alone except one patient with testicular abscess who underwent surgical drainage besides medical treatment. All patients recovered completely and no relapses have been detected during six-month follow-up. Conclusion: Patients with epididymo-orchitis should be investigated for brucellosis especially in endemic regions. To our knowledge, BEO patients may present with isolated testicular symptoms that make a diagnostic challenge.Öğe Brucellar prosthetic aortic valve endocarditis(Elsevier Science Inc, 2023) Gözdaş, Hasan Tahsin; Şahin, Sultan Beste; Uçaroğlu, Erhan RenanTo the Editor: A 56-year-old man was admitted to the cardiology outpatient clinic with a chief complaint of progressive dyspnea. His past medical history was remarkable for diabetes mellitus, essential hypertension, coronary artery disease, and left hemiplegia due to a cerebrovascular event. He also underwent prosthetic aortic valve replacement 16 years ago.Öğe Brucellosis presented with fever and generalized maculopapular rash(Erciyes Univ Sch Medicine, 2020) Gözdaş, Hasan Tahsin; Sırmatel, Fatma; Akdeniz, HayrettinBackground: Brucellosis is a multisystemic zoonosis that can affect all body organs and systems. Musculoskeletal system is the most affected system; however, cutaneous involvement is quite rare. Case Report: A 31-year-old male who was previously healthy was admitted with fever and generalized maculopapular rash for the last three days before his admission to the hospital. He was eventually diagnosed with brucellosis based on the clinical history and epidemiological features. Brucellosis treatment was administered for six weeks and the patient recovered completely. Conclusion: In endemic regions, brucellosis should be included in the differential diagnosis of the patients presenting with fever and generalized maculopapular rash.Öğe C-reactive protein and neutrophil-lymphocyte ratio as predictors of mortality in coronavirus disease 2019(ASSOC MEDICA BRASILEIRA, 2021) Ergenç, Hasan; Ergenç, Zeynep; Doğan, Muharrem; Usanmaz, Mustafa; Gözdaş, Hasan TahsinOBJECTIVE: This study investigates whether C-reactive protein, platelet-lymphocyte ratio, and neutrophil-lymphocyte ratio could be useful to predict mortality in COVID-19. METHODS: Data of 635 patients with COVID-19 followed up in Sinop Ataturk State Hospital from February to May 2020 were evaluated retrospectively. Diagnosis of COVID-19 was made according to the interim guidance of the World Health Organization. Patients were grouped into two groups based on mortality as survived and non-survived patients. Age, gender, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and C-reactive protein of the groups were investigated and compared. RESULTS: The mean age of the participants was 55.8 +/- 22.3 years. Among the patients, 584 survived and 51 patients died. Age was significantly different between the groups, 54.2 +/- 22.3 in the survived group and 75.6 +/- 11.1 in the dead group (p=0.000). In addition, neutrophil, C-reactive protein, and neutrophil-lymphocyte ratio values were significantly higher in the dead group (p=0.000). platelet-lymphocyte ratio was slightly higher in the dead group, but this difference was not significant (p=0.42). The area under the curve values for age, lymphocyte, platelet, C-reactive protein, and neutrophil-lymphocyte ratio are 0.797, 0.424, 0.485, 0.778, and 0.729, respectively. CONCLUSIONS: Our results showed that neutrophil-lymphocyte ratio and C-reactive protein are significantly higher in patients leading to death and could be effective biomarkers in predicting COVID-19 fatality. Furthermore, C-reactive protein could be used as an independent biomarker to predict death in patients with COVID-19, regardless of gender and age (p=0.000).Öğe Can it be osteoarticular involvement in the brucellosis?(Taylor & Francis Ltd, 2023) Gözdaş, Hasan Tahsin; Bal, TayibeLetterÖğe Comment on: "evaluation of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio in patients with cellulitis"(Assoc Medica Brasileira, 2020) Gözdaş, Hasan TahsinEasily accessible hemogram-derived parameters have gained the attention of physicians recently. These are simple, practical, and economical parameters that were found useful in the prediction of many clinical problems. They are often used as a sign of chronic inflammation. In chronic inflammatory conditions, their levels are elevated. Chronic inflammation has been linked with the pathogenesis of many different diseases and their complications. Neutrophil to lymphocyte ratio (NLR) is one of the most important and popular hemogram biomarkers showing chronic inflammation.Öğe Concomitant Bilateral Sacroiliitis and Lumbar Spondylodiscitis Secondary to Staphylococcus aureus Sepsis(2020) Gözdaş, Hasan Tahsin; Hızal, MustafaA 59-year-old man presented to our hospital with a one-week history of fever and progressive lumbar and gluteal pain. He was a farmer and had a previous medical history of lumbar disc hernia. He mentioned that he lifted heavy loads. During the physical examination, his gluteal and lumbar joint movements were extremely restricted; thus, he was unable to actively move and walk due to severe pain. Laboratory findings were as follows: white blood cells, 25.6 K/uL (n=4.5–11); neutrophils, 18.8 K/uL (n=1.8–7.3); alanine aminotransferase, 139 U/L (n=0–55); aspartate aminotransferase, 113 U/L (n=5–34); C-reactive protein, 173.9 mg/L (n=0–5); erythrocyte sedimentation rate, 101 mm/h (n=0–15). He was admitted to the inpatient clinic with a presumptive diagnosis of lumbar spondylodiscitis. After obtaining blood cultures, the intravenous administration of 4×1.5-g ampicillin–sulbactam was initiated. The Rose Bengal, Wright tube agglutination, and tuberculin skin tests were negative.Öğe Elevated mean platelet volume to platelet ratio predicts advanced fibrosis in chronic hepatitis C(Lippincott Williams & Wilkins, 2020) Gözdaş, Hasan Tahsin; İnce, NevinObjective Chronic hepatitis C virus (HCV) infection is an important health problem that can cause liver cirrhosis and hepatocellular carcinoma. Recently, novel inflammatory markers from complete blood count have been used as a precursor of many clinical conditions. In this study, we investigated the role of hemogram parameters in predicting advanced liver fibrosis in chronic HCV patients. Methods Patients who underwent percutaneous liver biopsy due to chronic HCV infection between 01.01.2011 and 01.08.2019 were included in this study. Liver biopsies were evaluated according to Ishak method. Patients were classified into those with mild fibrosis (F <= 2) and advanced fibrosis (F >= 3). Hemogram parameters of these groups were compared and their efficacy in predicting severe fibrosis was investigated. Results Of the 81 chronic HCV patients, 38 cases were in the mild fibrosis group and 43 cases were in the severe fibrosis group. Mean platelet volume, mean platelet volume to lymphocyte ratio, mean platelet volume to platelet ratio, and red cell distribution width to platelet ratio of the severe fibrosis group were significantly higher than those of the mild fibrosis group (P < 0.05 for all). In the ROC curve analysis, mean platelet volume to platelet ratio showed the biggest area under the curve in the prediction of advanced fibrosis. Conclusion Mean platelet volume to platelet ratio may be an easy and practical biomarker to gain a preliminary insight into advanced fibrosis in chronic HCV patients.Öğe Evaluation of Clinical and Epidemiological characteristics of Tularemia suspected cases in Kastamonu between 2014-2017 years(2019) Gözdaş, Hasan Tahsin; Göksel, Abdullah OnurAim: Tularemia is a zoonosis caused by Francisella tularensis. It appears as local outbreaks or sporadic cases. The aim of this study was to evaluate tularemia suspected cases in terms of clinical and epidemiological characteristics during admission. Material and Methods: Thirty six tularemia suspected cases were evaluated retrospectively in terms of clinical and epidemiological characteristics between 2014-2017 years. Diagnosis was made when tularemia microagglutination test was positive at 1/160 titer and above. Results: Among 36 suspected patients, four (11%) was diagnosed with tularemia. Of the total four cases diagnosed with tularemia, three applied in 2017 (two cases in February, one in April) and the other one applied at the end of 2016 (December). Among the patients applied in 2017, two of them applied in February and the other one in April. Oropharyngeal form was detected in two patients, glandular form in one and oculoglandular form in one. All of the tularemia cases came from the same region (Cide district). History of three patients included the presence of alive or dead mouse, rabbit or rodent in the environment of home. Conclusion: Tularemia should be considered in the differential diagnosis of patients with cervical lymphadenopathy who came from risky places especially in winter season. In endemic areas, knowledge of annual and monthly distribution of tularemia cases may be useful in providing early diagnosis to risk groups.Öğe Factors affecting cervical lymph node suppuration in oropharyngeal tularemia cases(COLL PHYSICIANS & SURGEONS PAKISTAN, 2021) İnce, Nevin; Gözdaş, Hasan TahsinObjective: To determine the factors associated with cervical lymph node suppuration in oropharyngeal tularemia. Study Design: Observational study. Place and Duration of Study: Departments of Infectious Diseases and Clinical Microbiology, Faculties of Medicine, Duzce University and Bolu Abant Izzet Baysal University Turkey, between January 2016 and August 2019. Methodology: Tularemia was diagnosed in clinically compatible cases by micro-agglutination test (>= 1/ 160 titres). Positive cases were divided into two groups according to development of suppurated and discharging lymph nodes. If the cases did not develop suppuration and discharge lymph nodes, they were defined as completely healed. If they did, they were defined as suppurated and drained lymph node group. Demographic and clinical characteristics and acute phase reactants of these groups were compared as to investigate any significant difference between the groups. Results: There were 88 tularemia cases in the current study. Of these, 60 cases were completely healed (68.2%) and 28 cases had suppurated and drained lymph nodes (31.8%). Tonsillopharyngitis was found significantly lower in suppurated and drained lymph node group compared to the completely healed group (p= 0.016). However, late presentation (>14 days) was found significantly more frequent in suppurated and drained lymph node group compared to the completely healed group (p=0.033). Conclusion: In order to prevent suppurative lymphadenitis in oropharyngeal tularemia, it is advisable to start appropriate antimicrobials within 14 days after the appearance of symptoms.Öğe Fournier’s gangrene: Review of 36 cases(2019) Çalışkan, Selahattin; Özsoy, Emrah; Sungur, Mustafa; Gözdaş, Hasan TahsinBACKGROUND: Fournier’s gangrene (FG) is a very rare disease in daily urological practice. Despite medical improvements, mortality in FG is still high. Early diagnosis is very important to reduce additional instrumentations and mortality. In this study, we aimed to present the characteristics of the patients with Fournier’s gangrene followed in two centers during ten years period. METHODS: The medical records of patients with FG were reviewed retrospectively. The patient characteristics, causative pathogens, laboratory findings and treatment modalities were evaluated. RESULTS: A total of 36 FG cases admitted between January 2008 and February 2018 were included in this study, consisting of 35 male patients, and one female patient with a mean age of 59.27±12.91 years. The mean duration of hospital stay was 19±10.44 days. The most common predisposing factor was diabetes mellitus, which was found in 28 patients. Malignancy was detected in three patients; prostate cancer in two patients and chronic lymphoblastic leukemia in one patient. Two patients had liver cirrhosis, and one patient had Behcet’s disease and psoriasis. The microbiological agent was isolated from a wound culture in nine patients. After urgent surgical debridement, daily dressing with nitrofurazone (Furacin) was done. Additional debridement was conducted when necessary. Orchiectomy was performed in 10 patients; two of them underwent bilateral orchiectomy. One patient died because of sepsis on the seventh day of hospital admission. CONCLUSION: FG is a life-threatening urological emergency with a high mortality rate. Treatment with broad-spectrum antibiotics and urgent surgery is pivotal for the prevention of mortality.Öğe Images in vascular medicine: Sudden mental status change and speech disturbance due to aortic echinococcosis(SAGE Publications Ltd, 2023) Uçaroğlu, Erhan Renan; Gözdaş, Hasan Tahsin; Yılmazsoy, Yunus; Özçelik, Hüsna; Korkmaz, Ufuk Turan Kürşat; Erdem, KemalettinA 52-year-old man presented to our center with speech disorder which occurred after temporary loss of consciousness that lasted nearly 10 seconds and was repeated twice. He had a history of cerebrovascular event nearly 2 months ago. He was conscious and had no acute distress.Öğe Investigation of a healthcare-associated candida infections in a Turkish intensive care unit: risk factors, therapy and clinical outcome(2021) Avcioğlu, Fatma; Sirmatel, Fatma; Behcet, Mustafa; Ozarslan, Oğulcan; Gözdaş, Hasan TahsinAim: Candida infections develop especially in intensive care unit (ICU) patients and increase the mortality rates. So, early and accurate diagnosis of Candida infections and determination of risk factors are very important. We aimed to retrospectively investigate Candida infections in terms of species and risk factors for candidemia caused by fungi. Methods: Candida infections in critically ill patients hospitalized in the Intensive Care Unit of Bolu Abant Izzet Baysal University Training and Research Hospital between January 2014 and December 2018 were retrospectively analyzed. The isolated Candida species were evaluated according to the sample types. The cases were investigated in terms of mortality due to candidiasis, previously used antibiotics and isolated Candida species. Results: 34 Candida species isolated from fungal cultures in ICUs were included in the study. Candida albicans (73.5%) was the most prevalent species isolated (NAC 26.5%). Patients with Candida isolated in their urine samples (76%) had a higher mortality rate than patients with Candida from other regions. Conclusion: The results of our study suggest that the highest rate of candidiasis (88%) is in patients who received beta-lactam antibiotic treatment. In addition, we think that when Candida species are detected in the urine samples of critically ill patients in the ICU, care should be taken in terms of candidiasis.Öğe Is ceftriaxone a suitable option for the empirical treatment of postoperative pleural empyema?(Taylor & Francis Ltd, 2022) Gözdaş, Hasan TahsinTo the Editor,I read the article by Yagi et al. [1] recently appeared inyour journal with great interest. They described a case withpostoperative pleural empyema in their article. Ceftriaxonewas used in the empirical treatment of this case along withchest drainage. The most common etiological agents ofparapneumonic effusions and parapneumonic empyemaare pyogenic bacteria such asStreptococcus pneumoniae,oral streptococci, anaerobes andStaphylococcus aureusÖğe Monitoring, control and reduction of bioaerosols in the intensive care unit in Turkey(Ice Publishing, 2022) Lakestani, Sanaz; Çakır, İbrahim; Gözdaş, Hasan Tahsin; Yıldız, İsa; Demirhan, AbdullahMaintaining high indoor air quality in hospitals is important for protecting the health of both personnel and patients. In this study, the results of air quality monitoring carried out in the intensive care unit of a hospital in Bolu, Turkey, are discussed. Air disinfection devices were used to reduce the concentrations of bacteria. A 4-week sampling programme was implemented. In the first and the last weeks of the sampling, the disinfection devices were turned off, while in the second and third weeks, they were turned on. Bioaerosols were collected, and their indoor levels were determined by counting all plate colonies and bacterial types were identified by matrix-assisted laser desorption/ionisation-time of flight mass spectrometry. The highest levels of bacteria were measured in the mornings and before the air disinfection devices were turned on. Doctors did their rounds at approximately nine to ten o'clock. The dominant bacteria in the air samples examined were Staphylococcus hominis, Micrococcus luteus, Staphylococcus capitis, Staphylococcus epidermidis, Corynebacterium afermentans and Staphylococcus haemolyticus. The results showed that the air disinfection devices were effective in decreasing the concentration of microorganisms between 83.4 and 55% in the intensive care unit, which is very important for the healthcare staff and patients, particularly during pandemics.Öğe Multi-inflammatory index as a novel mortality predictor in critically Ill COVID-19 patients(Sage Publications Inc, 2022) Gözdaş, Hasan Tahsin; Kayış, Seyit Ali; Damarsoy, Tuğçe; Özsarı, Emine; Yıldız, İsa; Demirhan, AbdullahAim Systemic inflammation has a crucial role in the pathogenesis and mortality of Coronavirus disease 2019 (COVID-19). Multi-inflammatory index (MII) is a novel index related with systemic inflammation. In this study, we investigated the relationship between MII and in-hospital mortality in COVID-19 patients admitted to the intensive care unit (ICU). Methods We retrospectively analyzed the medical records of COVID-19 patients followed-up in the ICU of our institution between 01.04.2020 and 01.10.2021. Patients were classified into two groups according to mortality status as survivors and non-survivors. Various inflammatory parameters of the groups were compared and their efficacy in predicting mortality was investigated. Results Out of 348 study patients, 86 cases (24.7%) were in the survived group and 262 cases (75.3%) were in the dead group. The median age of the mortal group was significantly higher than that of the survived group (65.5 vs 76, P < .001). Multiple logistic regression analysis revealed that among all the included inflammatory parameters, MII showed the best efficacy for predicting mortality (OR: 0.999; 95% CI: 0.9991-0.9998; P = .003). Conclusion MII, a new combination of Neutrophil to lymphocyte ratio (NLR) and C-reactive protein (CRP), is a simple and practical biomarker that can help us in the prediction of mortality in COVID-19 patients followed-up in the ICU.Öğe An overlooked zoonotic disease: Retrospective evaluation of q fever seropositivity with clinical findings(Galenos Publ House, 2022) Sırmatel, Fatma; Kılıç, Selçuk; Kalaycıoğlu, Oya; Buçuk, Pınar; Özarslan, Talat Oğulcan; Damarsoy, Tuğçe; Gözdaş, Hasan TahsinIntroduction: Q fever is a zoonotic disease with a high seroprevalence in our region and a low awareness in our country. Patients who were diagnosed as having Q fever clinically, serologically, and radiologically during 2017-2020 were evaluated retrospectively and classified according to the organ involvement. Materials and Methods: The diagnosis was made according to the radiological, clinical and serological findings of the patient. The patients were distinguished as acute, acute/possible, and chronic/persistent according to phase I and phase II antibody titration. Serological studies were carried out via immune fluorescent method. Patients included in the study were evaluated in terms of age, gender, admission date, organ involvement, responses to treatment, and acute phase indicators. Results: A total of 107 patients were evaluated retrospectively. Sixty three patients (58.9%) were defined as having acute disease, 29 (27.1%) acute/ possible disease and 15 (14%) chronic/persistent disease. Patients with acute disease were admitted to the hospital in winter, patients with acute/ possible disease were admittedin summer/spring and patients with chronic/persistent disease in summer. Lung involvement was found in 45.8% of patients with positive Q fever serology, kidney involvement in 30.8%, neurological involvement in 29.9%, liver involvement in 22.4%, joint involvement in 18.7%, heart involvement in 5.6%, lymphadenomegaly in 4.7%, and bone involvement in 1.9%. Hepatic involvement was higher in patients with chronic/persistent disease (22.4%), while fever (39.7%) and muscle-joint pain (23.8%) were seen more frequently in patients with acute disease. There were no statistically significant differences in demographical data and levels of acute phase reactants. Conclusion: Since a non-routine test is used in the diagnosis of the disease, occupational exposure should be evaluated in complaints of unknown origin. The patients having unexplained organ involvement and elevated acute phase reactants should be examined serologically for Q fever, especially in endemic areas.Öğe Procalcitonin/albumin ratio as a novel biomarker for predicting mortality in COVID-19(JPMS Publication, 2022) Ergenç, Hasan; Ergenç, Zeynep; Öztürk, Cemal Koray; Gözdaş, Hasan Tahsin; Ocak, Özlem Karaca; İnce, ÖzgürBackground: Coronavirus disease 2019 (COVID-19) first appeared in China in December 2019, and has become a global pandemic. Because the clinical progression of the disease is highly variable, better prediction of prognosis and mortality is important. In the present study, we investigated the role of procalcitonin/albumin ratio (PAR) as a new biomarker in predicting mortality in patients with COVID-19 infection. Methods: In this study, patients with COVID-19 diagnosis were enrolled from Sakarya Yenikent State Hospital and Ayancik State Hospital between 09.11.2020 and 04.05.2021. The demographic characteristics, biochemical and hematological parameters such as age, gender, length of hospital stay, and comorbidities of the patients were collected retrospectively from medical records. Results: Of the 105 patients, 51 were mild and 54 were critically ill. Between mild and critical cases, age, lymphocyte count, red cell distribution width, neutrophile count, mean corpuscular volume (MCV), monocvte count, albumin, C-reactive protein, ferritin, procalcitonin, D-dimer, and PAR were statistically different (p<0.001 for all). All patients in the critical group and only 2% of the mild group died. PAR showed the largest area under the curve (0.949) for the prediction of mortality (p<0.001). Conclusion: We report that PAR, a simple, cheap, and easily accessible biomarker, can be used to predict the prognosis in patients with COVID-19 infection.
