Simple and fast pesticide nanosensors: Example of surface plasmon resonance coumaphos nanosensor

dc.authorid0000-0002-7006-5921en_US
dc.authorid0000-0003-0013-1310en_US
dc.authorid0000-0003-3260-1639en_US
dc.authorid0000-0002-6672-6862en_US
dc.authorid0000-0003-0161-172Xen_US
dc.contributor.authorOymen, Beste
dc.contributor.authorJalilzadeh, Mitra
dc.contributor.authorYılmaz, Fatma
dc.contributor.authorAşır, Süleyman
dc.contributor.authorTürkmen, Deniz
dc.contributor.authorDenizli, Adil
dc.date.accessioned2023-07-31T10:36:42Z
dc.date.available2023-07-31T10:36:42Z
dc.date.issued2023en_US
dc.departmentBAİBÜ, Gerede Meslek Yüksekokulu, Kimya ve Kimyasal İşleme Teknolojileri Bölümüen_US
dc.description.abstractHere, a molecular imprinting technique was employed to create an SPR-based nanosensor for the selective and sensitive detection of organophosphate-based coumaphos, a toxic insecticide/veterinary drug often used. To achieve this, UV polymerization was used to create polymeric nanofilms using N-methacryloyl-l-cysteine methyl ester, ethylene glycol dimethacrylate, and 2-hydroxyethyl methacrylate, which are functional monomers, cross-linkers, and hydrophilicity enabling agents, respectively. Several methods, including scanning electron microscopy (SEM), atomic force microscopy (AFM), and contact angle (CA) analyses, were used to characterize the nanofilms. Using coumaphos-imprinted SPR (CIP-SPR) and non-imprinted SPR (NIP-SPR) nanosensor chips, the kinetic evaluations of coumaphos sensing were investigated. The created CIP-SPR nanosensor demonstrated high selectivity to the coumaphos molecule compared to similar competitor molecules, including diazinon, pirimiphos-methyl, pyridaphenthion, phosalone, N-2,4(dimethylphenyl) formamide, 2,4-dimethylaniline, dimethoate, and phosmet. Additionally, there is a magnificent linear relationship for the concentration range of 0.1-250 ppb, with a low limit of detection (LOD) and limit of quantification (LOQ) of 0.001 and 0.003 ppb, respectively, and a high imprinting factor (I.F.4.4) for coumaphos. The Langmuir adsorption model is the best appropriate thermodynamic approach for the nanosensor. Intraday trials were performed three times with five repetitions to statistically evaluate the CIP-SPR nanosensor's reusability. Reusability investigations for the two weeks of interday analyses also indicated the three-dimensional stability of the CIP-SPR nanosensor. The remarkable reusability and reproducibility of the procedure are indicated by an RSD% result of less than 1.5. Therefore, it has been determined that the generated CIP-SPR nanosensors are highly selective, rapidly responsive, simple to use, reusable, and sensitive for coumaphos detection in an aqueous solution. An amino acid, which was used to detect coumaphos, included a CIP-SPR nanosensor manufactured without complicated coupling methods and labelling processes. Liquid chromatography with tandem mass spectrometry (LC/MS-MS) studies was performed for the validation studies of the SPR.en_US
dc.identifier.citationOymen, B., Jalilzadeh, M., Yılmaz, F., Aşır, S., Türkmen, D., & Denizli, A. (2023). Simple and Fast Pesticide Nanosensors: Example of Surface Plasmon Resonance Coumaphos Nanosensor. Micromachines, 14(4), 707.en_US
dc.identifier.doi10.3390/mi14040707
dc.identifier.endpage16en_US
dc.identifier.issn2072-666X
dc.identifier.issue4en_US
dc.identifier.pmid37420940en_US
dc.identifier.scopus2-s2.0-85158167156en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://dx.doi.org/10.3390/mi14040707
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11404
dc.identifier.volume14en_US
dc.identifier.wosWOS:000976724000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYılmaz, Fatma
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofMicromachinesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMolecular Imprintingen_US
dc.subjectSurface Plasmon Resonanceen_US
dc.subjectNanosensoren_US
dc.subjectNanofilmen_US
dc.subjectCoumaphosen_US
dc.subjectResiduesen_US
dc.titleSimple and fast pesticide nanosensors: Example of surface plasmon resonance coumaphos nanosensoren_US
dc.typeArticleen_US

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