Fruits of Rosaceae family as a source of anticancer compounds and molecular innovations

dc.authorid0000-0002-9375-7365
dc.authorid0000-0002-7694-9859
dc.authorid0000-0003-0387-7599
dc.authorid0000-0002-8524-9029
dc.contributor.authorSameeullah, Muhammad
dc.contributor.authorGündoğdu, Muttalip
dc.contributor.authorCanan, ihsan
dc.contributor.authorKaradeniz, Turan
dc.contributor.authorAasim, Muhammad
dc.date.accessioned2021-06-23T18:51:32Z
dc.date.available2021-06-23T18:51:32Z
dc.date.issued2018
dc.departmentBAİBÜ, Ziraat Fakültesi, Bahçe Bitkileri Bölümüen_US
dc.description.abstractFruits of the family, Rosaceae (Apple, cherry, Peach, strawberry, rose, raspberry) are rich source of phenolic and antioxidant compounds having anticancer properties. The present chapter discusses the detail information about anticancer compounds of strawberry, raspberry, peach, apple, cherry and rose and also the genes responsible for the biosynthesis, accumulation and transport of anticancer compounds during growth and maturation of fruits. The transcriptome expression was performed to find putative genes responsible for anticancer compounds during the biosynthesis and transporter genes. It is revealed form the promoter analysis that cis-acting element is responsible for the regulation of anticancer compounds. Thus, CRISPR/Cas9 enhanced the biosynthesis of anticancer compounds during fruit development and maturation stages. CRISPR/Cas9 will be used for the silencing of genes which putatively inhibit the formation of anti-cancer compounds and also up-regulate biosynthesis and transporter genes mediated by CRISPR/Cas9to enhance their accumulation in these fruits. © Springer Nature Singapore Pte Ltd. 2018.en_US
dc.description.urihttps://link.springer.com/chapter/10.1007/978-981-10-8417-1_13
dc.identifier.doi10.1007/978-981-10-8417-1_13
dc.identifier.endpage336en_US
dc.identifier.isbn9789811084171
dc.identifier.isbn9789811084164
dc.identifier.scopus2-s2.0-85063120688en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage319en_US
dc.identifier.urihttps://doi.org/10.1007/978-981-10-8417-1_13
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3844
dc.identifier.volume4en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSameeullah, Muhammad
dc.institutionauthorGündoğdu, Muttalip
dc.institutionauthorCanan, ihsan
dc.institutionauthorKaradeniz, Turan
dc.language.isoenen_US
dc.publisherSpringer Singaporeen_US
dc.relation.ispartofAnticancer Plants: Mechanisms and Molecular Interactionsen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidantsen_US
dc.subjectcis-acting elementsen_US
dc.subjectCRISPR/Cas9en_US
dc.subjectGene familiesen_US
dc.subjectPhenolicsen_US
dc.titleFruits of Rosaceae family as a source of anticancer compounds and molecular innovationsen_US
dc.typeBook Chapteren_US

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