Fruits of Rosaceae family as a source of anticancer compounds and molecular innovations
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Singapore
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Fruits of the family, Rosaceae (Apple, cherry, Peach, strawberry, rose, raspberry) are rich source of phenolic and antioxidant compounds having anticancer properties. The present chapter discusses the detail information about anticancer compounds of strawberry, raspberry, peach, apple, cherry and rose and also the genes responsible for the biosynthesis, accumulation and transport of anticancer compounds during growth and maturation of fruits. The transcriptome expression was performed to find putative genes responsible for anticancer compounds during the biosynthesis and transporter genes. It is revealed form the promoter analysis that cis-acting element is responsible for the regulation of anticancer compounds. Thus, CRISPR/Cas9 enhanced the biosynthesis of anticancer compounds during fruit development and maturation stages. CRISPR/Cas9 will be used for the silencing of genes which putatively inhibit the formation of anti-cancer compounds and also up-regulate biosynthesis and transporter genes mediated by CRISPR/Cas9to enhance their accumulation in these fruits. © Springer Nature Singapore Pte Ltd. 2018.
Açıklama
Anahtar Kelimeler
Antioxidants, cis-acting elements, CRISPR/Cas9, Gene families, Phenolics
Kaynak
Anticancer Plants: Mechanisms and Molecular Interactions
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
4
