Evaluation of total antioxidant and oxidant status in the serum of patients with seasonal allergic conjunctivitis.

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dc.authorid0000-0002-8249-2621
dc.contributor.authorDoğan, Ümit
dc.contributor.authorAğca, Sümeyra
dc.contributor.authorKıntekçe, Buket
dc.date.accessioned2021-06-23T18:51:34Z
dc.date.available2021-06-23T18:51:34Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractPurpose: To investigate the relationship between seasonal allergic conjunctivitis (SAC) and oxidative stress by measuring serum total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI). Methods: A total of 95 participants, 49 patients with SAC (18 female, 31 male) and age and gender matched 46 controls (23 female, 23 male) were included during allergy season in this observational case-control study. Serum samples were obtained from all participants. The measurements of serum TAS and TOS levels were made by automatic colorimetric method and OSI was calculated. Results: Serum TAS levels of the patient and control group were measured as 1.45 ± 0.19 mmol Trolox Equ/L and 1.46 ± 0.15 mmol Trolox Equ/L, respectively. The median serum TOS values of the patient and control group were 3.60 (1.34-36.27) µmol H2O2 Equ/L and 3.29 (1.00-12.96) µmol H2O2 Equ/L respectively. OSI values of the patient and control group were calculated as 37.67 ± 39.32 and 26.78 ± 15.38, respectively. There was no statistically significant difference between serum TAS, TOS and OSI values of two groups (p: 0.974, 0.544 and 0.372, respectively). Conclusion: We found no significant difference in levels of serum oxidative stress markers in patients with SAC and control group. There may be localized oxidative stress only in the ocular surface, which does not affect serum values in patients with SAC. © 2018, Scientific Publishers of India. All rights reserved.en_US
dc.identifier.doi10.4066/biomedicalresearch.29-17-3421
dc.identifier.endpage1051en_US
dc.identifier.issn0970-938X
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85045089421en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1048en_US
dc.identifier.urihttps://doi.org/10.4066/biomedicalresearch.29-17-3421
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3867
dc.identifier.volume29en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorDoğan, Ümit
dc.institutionauthorAğca, Sümeyra
dc.institutionauthorKıntekçe, Buket
dc.language.isoenen_US
dc.publisherScientific Publishers of Indiaen_US
dc.relation.ispartofBiomedical Research (India)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOxidative stress indexen_US
dc.subjectSeasonal allergic conjunctivitisen_US
dc.subjectTotal antioxidant statusen_US
dc.subjectTotal oxidant statusen_US
dc.titleEvaluation of total antioxidant and oxidant status in the serum of patients with seasonal allergic conjunctivitis.en_US
dc.typeArticleen_US

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