Mean platelet volume to lymphocyte ratio as a novel marker for diabetic nephropathy

Basit Öğe Kaydı
dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-3085-7964
dc.authorid0000-0001-7306-5233
dc.authorid0000-0002-3836-2125
dc.authorid0000-0003-4201-9757
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorAktaş, Gülali
dc.contributor.authorErkuş, Edip
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorAtak, Burçin Meryem
dc.date.accessioned2021-06-23T19:49:25Z
dc.date.available2021-06-23T19:49:25Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To compare mean platelet volume to lymphocyte ratio (MPVLR) of diabetic nephropathy subjects to those diabetics without diabetic nephropathy. Study Design: Observational, cross-sectional study. Place and Duration of Study: Tertiary referral hospital, in Bolu, Turkey, from July to December 2017. Methodology: Patients with type 2 diabetes mellitus admitted to the Internal Medicine Clinic, were included. Patients were divided into two groups according to the urinary microalbumin/creatinine ratio: diabetic nephropathy and non-nephropathy group. MPVLR was calculated mathematically by division of MPV by lymphocyte count. Results: There were 162 subjects (79 females, 83 males). The MPVLR in patients with diabetic nephropathy and non-nephropathic diabetic groups were 4.1 (2.09-11.84) and 3.4 (1.37-25.56), respectively. The difference was reached statistically significant level (p<0.001). The best cut-off value for MPVLR was 3.66 (AUC=0.733, p<0.001); MPVLR predicted diabetic nephropathy with 71.1% sensitivity and 67.4% specificity, at this level. Conclusion: The MPVLR is an easily calculated and efficient index that can be considered a powerful and independent predictor of diabetic nephropathy in diabetic patients. We suggest that, it can be useful adjunct to standard tests in the diagnosis of diabetic nephropathy.en_US
dc.identifier.doi10.29271/jcpsp.2018.11.844
dc.identifier.endpage847en_US
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue11en_US
dc.identifier.pmid30369376en_US
dc.identifier.startpage844en_US
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2018.11.844
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9494
dc.identifier.volume28en_US
dc.identifier.wosWOS:000449556100008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorAktaş, Gülali
dc.institutionauthorErkuş, Edip
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorAtak, Burçin Meryem
dc.language.isoenen_US
dc.publisherColl Physicians & Surgeons Pakistanen_US
dc.relation.ispartofJcpsp-Journal Of The College Of Physicians And Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetic Nephropathyen_US
dc.subjectInflammationen_US
dc.subjectMean Platelet Volume to Lymphocyte Ratioen_US
dc.titleMean platelet volume to lymphocyte ratio as a novel marker for diabetic nephropathyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
mehmet-zahid-kocak.pdf
Boyut:
543.73 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu