The frequency of scarring after genital ulcers in Behcet's syndrome: a prospective study

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dc.authorid0000-0002-5140-1926en_US
dc.authorid0000-0002-5738-336X
dc.authorid0000-0001-6745-4849
dc.contributor.authorMat, M. Cem
dc.contributor.authorGöksüğür, Nadir
dc.contributor.authorEngin, Burhan
dc.contributor.authorYurdakul, Sabahattin
dc.contributor.authorYazıcı, Hasan
dc.date.accessioned2021-06-23T19:19:12Z
dc.date.available2021-06-23T19:19:12Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Although genital ulceration with or without scar formation is an important manifestation of Behcet's syndrome, formal data on the rate of genital scarring are lacking. Objective To study prospectively the frequency of genital scar formation after genital ulcers in patients with Behcet's syndrome. Methods One hundred and two patients (72 males and 30 females) with fresh genital ulcers presenting at a dedicated Behcet's syndrome outpatient clinic were followed for 6 weeks. The ulcer location, size, and frequency of scar formation were noted. All patients were treated with similar topical therapy. Results Two hundred and ten genital ulcers were followed in both sexes. The rate of scar formation was 66.2% (102/154) in male patients and 60.7% (34/56) in female patients. When genital ulcers were stratified as a function of size, large genital ulcers (>= 1 cm in diameter) developed scars more frequently than did smaller ulcers (< 1 cm). The rate of scar formation in male patients with large genital ulcers was 89.4% (59/66) and with small ulcers was 48.9% (43/88) (P < 0.001). In females, all 19 large ulcers healed with scarring, and the same was true for 40.5% (15/37) of the small ulcers (chi(2) = 18.61, P < 0.001). Conclusion About two-thirds of genital ulcers in Behcet's syndrome leave scars. The rate of scar formation depends on the ulcer size.en_US
dc.identifier.doi10.1111/j.1365-4632.2006.02859.x
dc.identifier.endpage556en_US
dc.identifier.issn0011-9059
dc.identifier.issue5en_US
dc.identifier.pmid16700790en_US
dc.identifier.startpage554en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-4632.2006.02859.x
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5895
dc.identifier.volume45en_US
dc.identifier.wosWOS:000237181800012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGöksüğür, Nadir
dc.institutionauthorEngin, Burhan
dc.language.isoenen_US
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofInternational Journal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet Syndromeen_US
dc.subjectCicatrix
dc.subjectProspective Studies
dc.subjectCyclosporin A
dc.subjectGenital Ulcer
dc.titleThe frequency of scarring after genital ulcers in Behcet's syndrome: a prospective studyen_US
dc.typeArticleen_US

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