Synthesis of novel triazoles bearing 1,2,4-oxadiazole and phenylsulfonyl groups by 1,3-dipolar cycloaddition of some organic azides and their biological activities

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dc.authorid0000-0002-0873-694Xen_US
dc.authorid0000-0003-2739-7725
dc.authorid0000-0002-5650-1280
dc.contributor.authorDürüst, Yaşar
dc.contributor.authorKarakuş, Hamza
dc.contributor.authorYavuz, Muhsine Zeynep
dc.contributor.authorGepdiremen, Ali Akçahan
dc.date.accessioned2021-06-23T19:36:45Z
dc.date.available2021-06-23T19:36:45Z
dc.date.issued2014
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.description.abstract1,3-Dipolar cycloaddition of 5-azidomethyl-3-p-substituted phenyl-1,2,4-oxadiazoles to phenyl vinyl sulfone and bismaleimide gives rise straightforwardly to 1-((3-(p-substituted) phenyl-1,2,4-oxadiazol-5-yl)methyl)-4-(phenylsul-fonyl)- 4,5-dihydro-1 H -1,2,3-triazoles and bisdihydropyrrolo[3,4-d][1,2,3] triazole-4,6(3 a H, 5 H)-diones. The structures of the new cycloadducts were elucidated by means of IR, NMR (1 H, 1 3 C, 2D), mass spectra, and physical characteristics (mp and R f values). In addition, anticancer activities of the cycloadducts against MCF-7 cells were also investigated.en_US
dc.identifier.doi10.3906/kim-1309-59
dc.identifier.endpage755en_US
dc.identifier.issn1300-0527
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84907206923en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage739en_US
dc.identifier.trdizinid163460en_US
dc.identifier.urihttps://doi.org/10.3906/kim-1309-59
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8047
dc.identifier.volume38en_US
dc.identifier.wosWOS:000340769100006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorDürüst, Yaşar
dc.institutionauthorKarakuş, Hamza
dc.institutionauthorYavuz, Muhsine Zeynep
dc.institutionauthorGepdiremen, Ali Akçahan
dc.language.isoenen_US
dc.publisherScientific Technical Research Council Turkey-Tubitaken_US
dc.relation.ispartofTurkish Journal Of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAzideen_US
dc.subject1,3-dipolar Cycloadditionen_US
dc.subject1,2,4-oxadiazoleen_US
dc.subject1,2,3-triazoleen_US
dc.subjectPyrroleen_US
dc.subjectAnticancer Activityen_US
dc.titleSynthesis of novel triazoles bearing 1,2,4-oxadiazole and phenylsulfonyl groups by 1,3-dipolar cycloaddition of some organic azides and their biological activitiesen_US
dc.typeArticleen_US

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