The effect of serum and follicular fluid anti-Mullerian hormone level on the number of oocytes retrieved and rate of fertilization and clinical pregnancy

dc.authorid0000-0002-6326-7234
dc.contributor.authorBolat, Seda Eymen
dc.contributor.authorÖzdemirci, Şafak
dc.contributor.authorKasapoğlu, Taner
dc.contributor.authorDuran, Bülent
dc.contributor.authorGöktaş, Levent
dc.date.accessioned2021-06-23T19:43:59Z
dc.date.available2021-06-23T19:43:59Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: The objective of this study was to evaluate the relationship between oocyte yield, fertilization, and clinical pregnancy (CP), and anti-Mullerian hormone (AMH) level in serum and follicular fluid during in vitro fertilization treatment. METHODS: Forty-four infertile women who underwent IVF treatment using multiagonist protocol were included in this study. Baseline level of AMH in serum and follicular fluid was measured on third day of menstrual cycle. AMH level in serum and follicular fluid was then measured again on day of oocyte pick-up. Pearson correlation and binary regression tests were used for statistical analysis. For Type 1 error, p= 5% was selected as cut-off value for statistical significance. RESULTS: Serum AMH level was positively correlated with total number of oocytes retrieved and rate of fertilization and CP (r= 0.397, p= 0.008; r= 0.401, p= 0.007; and r= 0.382, p= 0.011, respectively). There was significantly negative correlation between serum level of follicle-stimulating hormone (FSH) and fertilization rate (r=-0.320; p= 0.034), as well as serum FSH level and CP rate (r=-0.308; p= 0.042). There were no significant correlations between AMH level in follicular fluid and IVF treatment outcomes. CONCLUSION: Serum AMH levels may be more reliable for prediction of total number of oocytes retrieved and rate of fertilization and CP than AMH levels in follicular fluid.en_US
dc.identifier.endpage96en_US
dc.identifier.issn2148-4902
dc.identifier.issue2en_US
dc.identifier.pmid28058394en_US
dc.identifier.startpage90en_US
dc.identifier.trdizinid263266en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8893
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000408979800002
dc.identifier.urihttps://www.journalagent.com/nci/pdfs/NCI_3_2_90_96.pdf
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpZek1qWTJOZz09
dc.identifier.volume3en_US
dc.identifier.wosWOS:000408979800002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDuran, Bülent
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofNorthern Clinics Of Istanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-Mullerian Hormone (AMH)en_US
dc.subjectClinical Pregnancyen_US
dc.subjectFertilizationen_US
dc.subjectFollicle-Stimulating Hormone (FSH)en_US
dc.subjectFollicular Fluiden_US
dc.subjectInfertilityen_US
dc.subjectIn Vitro Fertilizationen_US
dc.titleThe effect of serum and follicular fluid anti-Mullerian hormone level on the number of oocytes retrieved and rate of fertilization and clinical pregnancyen_US
dc.typeArticleen_US

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