Using of fibrinolytics in the treatment of complicated parapneumonic effusion and empyema in children

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dc.authorid0000-0003-4663-7157
dc.authorid0000-0002-8035-9923
dc.contributor.authorUyan, Ayten Pamukçu
dc.contributor.authorÖzyürek, Hamit
dc.contributor.authorYılmaz, Ebru
dc.date.accessioned2021-06-23T18:54:44Z
dc.date.available2021-06-23T18:54:44Z
dc.date.issued2003
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBacterial pneumonia is associated with a high incidence of pleural effusions in children. These parapneumonic effusions usually resolve spontaneously if patients are treated with appropriate antibiotics. However, a small percentage of parapneumonic effusions will become complicated, either loculated non-purulent fluid or an empyema. The traditional therapeutic approaches for complicated parapneumonic effusions includes catheter drainage and systemic antibiotics. Tube drainage often fails if the fluid is loculated by fibrinous adhesions and surgical operation require. Intrapleural administration of fibrinolytics is an effective treatment for complicated parapneumonic effusions and pleural empyemas, improving the drainage without causing systemic fibrinolysis or local hemorrhage. The global success rate were between 44% and 100%, in most cases more than 80%. Both streptokinase and urokinase have been used for this purpose but there are few reports of their use in the children. Intrapleural streptokinase and urokinase are equally efficacious in treating complicated parapneumonic effusions and empyemas. Intrapleural instillation of fibrinolytics is an effective and safe mode of treatment for complicated parapneumonic effusions and pleural empyemas, and may reduce the need for more invasive surgical procedures.en_US
dc.identifier.endpage324en_US
dc.identifier.issn0494-1373
dc.identifier.issue3en_US
dc.identifier.pmid15143413en_US
dc.identifier.scopus2-s2.0-16644376458en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage320en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4559
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-16644376458&partnerID=40&md5=fde4a5879003927b83783ef1bd7b4603
dc.identifier.volume51en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUyan, Ayten Pamukçu
dc.institutionauthorÖzyürek, Hamit
dc.institutionauthorYılmaz, Ebru
dc.language.isotren_US
dc.relation.ispartofTüberküloz ve toraksen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectParapneumonicen_US
dc.subjectEmpyema
dc.subjectChildren
dc.titleUsing of fibrinolytics in the treatment of complicated parapneumonic effusion and empyema in childrenen_US
dc.title.alternativeÇocuklarda komplike parapnömonik efüzyon ve ampiyem tedavisinde fibrinolitiklerin kullanımıen_US
dc.typeReview Articleen_US

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