Assessment of relation between neutrophil lympocyte, platelet lympocyte ratios and epicardial fat thickness in patients with ankylosing spondylitis

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dc.contributor.authorBoyraz, İsmail
dc.contributor.authorÇağlar, Sabri Onur
dc.contributor.authorErdem, Fatma
dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorYazıcı, Selma
dc.contributor.authorKoç, Bünyamin
dc.date.accessioned2021-06-23T18:51:47Z
dc.date.available2021-06-23T18:51:47Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim To investigate whether there is a relation between neutrophil-lymphocyte (N/L) and platelet- lymphocyte (P/L) ratios and epicardial adipose tissue (EAT) thickness in patients with ankylosing spondylitis (AS). Methods Thirty patients diagnosed with ankylosing spondylitis and 25 healthy people (controls) were included in the study. Age, gender, body mass index (BMI), height, hemogram, sedimentation, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, CRP, hepatic and renal function tests, lipid profile of the all patients were recorded. Data related to duration of the disease, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) values of the cases in the patient group were obtained. A cardiologist measured EAT thickness by ECHO in both patient and control groups. Results In the patient group, mean BASDAI and BASFI scores were 2.48±2.21 and 1.5±2.07, respectively. Age, gender, BMI values did not show statistically significant difference between the patient and the control groups. N/L and P/L ratios did not change significantly in the patient group having higher EAT, BASFI values and taking anti-TNF compared to the control group. Conclusion In patients with AS, EAT measurements, which are related to inflammatory response increase, can be used for monitoring of the risk of development of cardiac disease. We could not find the relation between EAT and N/L, P/L ratios in terms of evaluation of inflammatory response. © 2016, Medical Association of Zenica-Doboj Canton. All rights reserved.en_US
dc.identifier.doi10.17392/832-16
dc.identifier.endpage17en_US
dc.identifier.issn1840-0132
dc.identifier.issue1en_US
dc.identifier.pmid26827703en_US
dc.identifier.scopus2-s2.0-84957071593en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage14en_US
dc.identifier.urihttps://doi.org/10.17392/832-16
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3997
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBoyraz, İsmail
dc.institutionauthorÇağlar, Sabri Onur
dc.institutionauthorErdem, Fatma
dc.institutionauthorYazıcı, Mehmet
dc.institutionauthorYazıcı, Selma
dc.institutionauthorKoç, Bünyamin
dc.language.isoenen_US
dc.publisherMedical Association of Zenica-Doboj Cantonen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing spondylitisen_US
dc.subjectClinical markersen_US
dc.subjectInflammationen_US
dc.titleAssessment of relation between neutrophil lympocyte, platelet lympocyte ratios and epicardial fat thickness in patients with ankylosing spondylitisen_US
dc.typeArticleen_US

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