Comparison of toxin genes in staphylococcus aureus isolates obtained from patients and carriers

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dc.authorid0000-0003-0727-1797
dc.authorid0000-0002-3673-9670
dc.contributor.authorMengeloğlu, Fırat Zafer
dc.contributor.authorÇiçek, Ayşegül Çopur
dc.contributor.authorKoçoğlu, Esra
dc.contributor.authorTaş, Tekin
dc.contributor.authorBucak, Özlem
dc.contributor.authorGüçkan, Rıdvan
dc.date.accessioned2021-06-23T19:34:56Z
dc.date.available2021-06-23T19:34:56Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractIt is important to have information about virulence characteristics of S. aureus isolates obtained from the nasal cultures of carriers in terms of the capability to cause severe infections. In the present study, S. aureus isolates obtained from carriers and isolates obtained from clinical specimens, and which were determined as causative agents of infection, were compared in terms of the genes of staphylococcal enterotoxiiz A and 8 (sea and seb), TSST-I (tst), and PVL (pv1). A total of 44 S. aureus strains isolated from clinical specimens and 44 carrier isolates were tested for the genes with polyinerase chain reaction method. As the results, the most common gene was sea with a rate of 45.5% (40188). This gene was found in 34.1% (15144) of the carrier isolates and in 56.8% (25144) of the clinical group. Furthermore, the presence of the sea gene was found to be significantly higher in the clinical isolates than in the carriers' (P=0.032). The tst, seb, and pvl genes were positive at rates of 18.2% (16188). 4.5% (4188), and 5.7% (5188), respectively. No significant differences were found between the groups according to positivity rates of the tst, seb, and pvl genes (p>0.05 for each gene) To our knowledge, differences between carrier isolates and clinical isolates in terms of toxin genes have not been investigated before the present study. The presence of sea at a significantly higher rate in clinical isolates shows the need for advanced molecular analysis on this topic.en_US
dc.identifier.endpage664en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84896716612en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage659en_US
dc.identifier.urihttps://www.actamedicamediterranea.com/archive/2013/medica-4/comparison-of-toxin-genes-in-staphylococcus-aureus-isolates-obtained-from-patients-and-carriers
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7666
dc.identifier.volume29en_US
dc.identifier.wosWOS:000330151200009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorMengeloğlu, Fırat Zafer
dc.institutionauthorKoçoğlu, Esra
dc.institutionauthorBucak, Özlem
dc.institutionauthorTaş, Tekin
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStaphylococcus Aureusen_US
dc.subjectToxin Geneen_US
dc.subjectStaphylococcal Enterotoxinen_US
dc.subjectPVLen_US
dc.subjectToxic Shock Syndrome Toxin-1en_US
dc.subjectCarrieren_US
dc.titleComparison of toxin genes in staphylococcus aureus isolates obtained from patients and carriersen_US
dc.typeArticleen_US

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