Serum level of nt-probnp as an early cardiac marker of carbon monoxide poisoning

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dc.authorid0000-0003-1604-9565
dc.authorid0000-0002-3041-7427
dc.authorid0000-0002-4005-8157
dc.authorid0000-0002-0363-9307
dc.authorid0000-0003-1313-6903
dc.authorid0000-0002-2398-8264
dc.contributor.authorDavutoğlu, Vedat
dc.contributor.authorGünay, Nurullah
dc.contributor.authorKoçoğlu, Hasan
dc.contributor.authorGünay, Nahide Ekici
dc.contributor.authorYıldırım, Cuma
dc.contributor.authorÇavdar, Murat
dc.contributor.authorTarakcıoğlu, Mehmet
dc.date.accessioned2021-06-23T18:54:22Z
dc.date.available2021-06-23T18:54:22Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction Acute carbon monoxide (CO) poisoning may cause cardiotoxicity. The natriuretic peptides that include atrial natriuretic peptide, brain natriuretic peptide (BNP), N-BNP and NT-proBNP are endogenous cardiac hormones that may be secreted upon myocardial stress [1]. The aim of this study was to assess the plasma NT-proBNP level in acute CO poisoning, and to compare it with healthy controls. Material and methods After approval of the ethical committee, patients with the diagnosis of carbon monoxide poisoning were studied. Echocardiography was performed to all patients [2–4]. Serum NT-pro BNP, creatine kinase (CK), creatine kinase-MB (CK-MB) and Troponin-T were also analyzed together with the carboxyhemoglobin (COHb) level. The correlation between serum NT-pro BNP and COHb level was investigated. All tests were performed other than COHb in the blood of healthy volunteers. Electrocardiograms were performed in all patients and healthy controls, and the results were compared. Results Troponin, CK and CK-MB levels were statistically insignificant between both groups (P>0.05). The level of NT-proBNP and COHb were found to be increased in the study group. A positive correlation was found between the COHb and the NT-proBNP (r=0.829, P<0.01), and between the COHb and the CK (r=0.394, P<0.01). No difference was observed in other parameters between groups all of which were within normal range. Conclusion We conclude that, being an early increasing marker, measuring the plasma NT-proBNP level may contribute to the early diagnosis of cardiotoxicity in patients with carbon monoxide poisoning, contributory to the conventional methodsen_US
dc.identifier.doi10.1097/00063110-200610000-00055
dc.identifier.endpage1984en_US
dc.identifier.issn0969-9546
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85026149171en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1983en_US
dc.identifier.urihttps://doi.org/10.1097/00063110-200610000-00055
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4397
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKoçoğlu, Hasan
dc.language.isoenen_US
dc.relation.ispartofEuropean Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keywords]en_US
dc.titleSerum level of nt-probnp as an early cardiac marker of carbon monoxide poisoningen_US
dc.typeArticleen_US

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