A case of sitagliptin-induced mild acute pancreatitis

Acute pancreatitis (AP) is characterised by inflammatory destruction of the gland due to early activation of the pancreatic proteolytic enzymes. Drug-induced AP accounts for only 0.1-2 % of AP.1 One of these drugs is dipeptidyl peptidase-4 inhibitor (DPP-4i). Association between AP and Sitagliptin, a DPP-4i, was initially described in a transgenic rat model.2 We aim to present a case of AP in a diabetic elderly, which was likely associated with Sitagliptin treatment.