The relationship between total standardized mini mental state examination (SMMSE) and subscores and D vitamin, folate and B12 levels in patients with cognitive dysfunction

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dc.authorid0000-0001-8616-832X
dc.authorid0000-0002-9647-4432
dc.authorid0000-0001-5524-5767
dc.contributor.authorTürkoğlu, Şule Aydın
dc.contributor.authorÖgün, Muhammed Nur
dc.contributor.authorMiçooğulları, Evgin
dc.contributor.authorGültekin, Edip
dc.contributor.authorYıldız, Serpil
dc.date.accessioned2021-06-23T18:51:38Z
dc.date.available2021-06-23T18:51:38Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: There is evidence that low vitamin levels may be associated with cognitive functions, results from studies on this issue have been incoherent. This study aimed to evaluate whether there is any relationship between the levels of Vitamin D, Folate and B12 and Standardized Mini-Mental Test (SMMT) and subgroups in patients with cognitive dysfunction. Methods: This retrospective study included 184 women and 89 men with cognitive problems and who had SMMSE scores of 24/30 or less. SMMSE scores were prospectively recorded in the patient's file for each patient by an experienced neuropsychologist. SMMSE scores were prospectively recorded in the patient's file for each patient by an experienced neuropsychologist. Vitamin B12, vitamin D and Folate levels were studied from 10:00 am fasting blood samples of each patient and prospectively recorded in patient file. Patient files were retrospectively reviewed and data were recorded. Results: No correlation was found between vitamin D and vitamin B12 levels and SMMSE (total and sub scores) in both sexes. Folate levels were significantly correlated with the SMMSE total (p=0.005, r=0.288), orientation (p=0.004, r=0.290) and registration (p=0.04, r=0.215) scores in females. A positive correlation was found between the folate levels and the SMMSE recall sub score in both sexes (p=0.002, r=0.227). Conclusions: Folate deficiency is an easily treatable condition. Thus it should be considered in the differential diagnosis of cognitive impairment especially in female patients. © 2017, Scientific Publishers of India. All rights reserved.en_US
dc.identifier.endpage9897en_US
dc.identifier.issn0970-938X
dc.identifier.issue22en_US
dc.identifier.scopus2-s2.0-85042261974en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage9894en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3921
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85042261974&partnerID=40&md5=92e65fc50a35ca2e3e74cc5d025b50e0
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTürkoğlu, Şule Aydın
dc.institutionauthorÖgün, Muhammed Nur
dc.institutionauthorMiçooğulları, Evgin
dc.institutionauthorGültekin, Edip
dc.language.isoenen_US
dc.publisherScientific Publishers of Indiaen_US
dc.relation.ispartofBiomedical Research (India)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCognitive disunctionen_US
dc.subjectFolateen_US
dc.subjectSMMSEen_US
dc.subjectVitamin B12en_US
dc.subjectVitamin Den_US
dc.titleThe relationship between total standardized mini mental state examination (SMMSE) and subscores and D vitamin, folate and B12 levels in patients with cognitive dysfunctionen_US
dc.typeArticleen_US

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