Roles of citrus fruits on energy expenditure, body weight management, and metabolic biomarkers: A comprehensive review
Yükleniyor...
Dosyalar
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Oxford University Press Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Citrus fruits are widely consumed for their nutritional and health benefits. They belong to the Rutaceae and have many varieties, such as sweet orange (Citrus sinensis), which is the most popular. Citrus fruits are rich in water (>80%), dietary fiber, and vitamins. They also contain bioactive components, which may modulate energy metabolism and lipid oxidation through various mechanisms. These mechanisms include stimulating b3-adrenergic receptors, increasing mitochondrial biogenesis and thermogenesis, activating AMP kinase and peroxisome proliferatoractivated receptor-gamma coactivator-1a pathways, inhibiting lipogenesis and lipid accumulation, and inducing browning of white adipose tissue. This review summarizes the mechanisms and outcomes of citrus fruits and their metabolites on energy metabolism and body weight in different experimental models. The literature was searched for in vitro and in vivo animal and human studies that investigated the effects of citrus consumption on energy expenditure, thermogenesis, adipogenesis, and lipid accumulation. Citrus fruits and their metabolites have shown promising effects on energy metabolism and lipid oxidation in in vitro and in vivo animal studies. However, the evidence from human studies is limited and inconsistent. Possible reasons for the discrepancy are briefly discussed, and knowledge gaps and research needs are identified for future studies. Citrus fruits may have beneficial effects on energy metabolism and body weight, but more rigorous and welldesigned human trials are needed to confirm their efficacy and safety.
Açıklama
The authors thank the Gazi University proof team for checking the academic writing of the article.r Author contributions. M.N.A. and B.S.-K. contributed equally to this study and contributed to the conception, design, investigation, data curation, visualization, writing, preparation of tables and figures, review, and editing. N.A.T. contributed to the conception, design, critical revision, project administration, and supervision of the study. All authors have read and approved the final version of the manuscript.
Anahtar Kelimeler
Adipogenesis, Citrus, Energy Metabolism, Orange Juice Consumption, Aurantium Bitter Orange, Fat Oxidation Rate
Kaynak
Nutrition Reviews
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
Sayı
Künye
Aslan, M. N., Sukan-Karaçağıl, B., & Acar-Tek, N. (2023). Roles of citrus fruits on energy expenditure, body weight management, and metabolic biomarkers: a comprehensive review. Nutrition Reviews, nuad116.
