Effects of extra corporeal shock wave lithotripsy on portal vein cytokine levels, and liver

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dc.authorid0000-0001-7069-0623en_US
dc.authorid0000-0002-1436-090X
dc.authorid0000-0001-6990-185X
dc.authorid0000-0002-0317-7181
dc.contributor.authorArıkan, Yüksel
dc.contributor.authorŞenel, M. Ferda
dc.contributor.authorGünal, Ömer
dc.contributor.authorPehlivan, Mevlüt
dc.contributor.authorAlper, Murat
dc.date.accessioned2021-06-23T19:17:21Z
dc.date.available2021-06-23T19:17:21Z
dc.date.issued2000
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionEurosurgery 2000 Meeting -- JUN 21-24, 2000 -- ISTANBUL, TURKEYen_US
dc.description.abstractWe aimed to determine the effect of shock waves on the liver tissue, as well as on the portal vein IL-6 and TNF alpha levels.. The rats in the control group (n:10) did not receive any shock waves, while other rats (n:10) received 1000 shock waves. Twenty four hours after administration of shock waves all rats were sacrified and livers were taken out for histopathological evaluation. In addition portal vein IL-6 and TNF alpha serum levels were assayed. The mean IL-6 and TNF alpha levels of rats receiving shock waves ESWL were 276+/-10,7 pg / mi and 230+/-12,8 pg/ml respectively, These were significantly higher than that of the control group (p<0,05). The mean liver damage scores in this group (3,3+/-0,3) was also significantly higher than the control group (0,3+/-0,1; p<0.01), Histopathological examination of the livers revealed mild venous congestion, kupper cell hyperplesia, and erythrocyte extravasation in the sinusoids. As the safety range of shock wave administration to liver seems to be narrow we suggest low dose treatment for intrahepatic bile stones. In addition, early cytokine levels might be good indicators of the tissue damage, and guide us to determine the safety margin of shock wave administration.en_US
dc.identifier.endpage25en_US
dc.identifier.isbn88-323-0621-2
dc.identifier.startpage21en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5367
dc.identifier.wosWOS:000089220200005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorArıkan, Yüksel
dc.institutionauthorGünal, Ömer
dc.institutionauthorPehlivan, Mevlüt
dc.institutionauthorAlper, Murat
dc.language.isoenen_US
dc.publisherMedimond S R Len_US
dc.relation.ispartofProceedings Eurosurgery 2000en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExtra Corporeal Shocken_US
dc.subjectLithotripsy
dc.titleEffects of extra corporeal shock wave lithotripsy on portal vein cytokine levels, and liveren_US
dc.typeConference Objecten_US

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