Which one is more effective, filgrastim or lenograstim, during febrile neutropenia attack in hospitalized patients with solid tumors?

Basit Öğe Kaydı
dc.authorid0000-0002-6839-2632
dc.authorid0000-0002-6665-9000
dc.authorid0000-0003-2860-2831
dc.contributor.authorSönmez, Özlem Uysal
dc.contributor.authorGüçlü, Ertuğrul
dc.contributor.authorÜyetürk, Ümmügül
dc.contributor.authorEsbah, Oruç
dc.contributor.authorTürker, İbrahim
dc.date.accessioned2021-06-23T18:55:10Z
dc.date.available2021-06-23T18:55:10Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Chemotherapy-induced febrile neutropenia (FN) with solid tumors causes mortality and morbidity at a significant rate. The purpose of this study was to compare the effects of filgastrim and lenograstim started with the first dose of antibiotics in hospitalized patients diagnosed with FN. Materials and Methods: Between February 2009 and May 2012, 151 patients diagnosed with FN were evaluated, retrospectively. In those considered appropriate for hospitalization, convenient antibiotic therapy with granulocyte colony stimulating factors was started within first 30 minutes by completing necessary examinations in accordance with FEN guide recommendations. Results: In this study, 175 febrile neutropenia attacks in 151 patients were examined. Seventy three of the patients were male and 78 were female. The average age was 53.6 and 53.6, respectively. The most common solid tumor was breast carcinoma in 38 (25%) . One hundred and five FN patients (58%) were those who received granulocyte colony stimulating factors as primary prophylaxis. Conclusions: While studies comparing both drugs generally involve treatments started for prophylaxis, this study compared the treatment given during the febrile neutropenia attack. Compared to lenograstim, filgastrim shortens the duration of hospitalization during febrile neutropenia attack by facilitating faster recovery with solid tumors.en_US
dc.identifier.doi10.7314/APJCP.2015.16.3.1185
dc.identifier.endpage1189en_US
dc.identifier.issn1513-7368
dc.identifier.issue3en_US
dc.identifier.pmid25735353en_US
dc.identifier.scopus2-s2.0-84929315936en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1185en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2015.16.3.1185
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4699
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÜyetürk, Ümmügül
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFebrile Neutropeniaen_US
dc.subjectFilgrastimen_US
dc.subjectLenograstimen_US
dc.subjectRecoveryen_US
dc.subjectSolid tumoren_US
dc.titleWhich one is more effective, filgrastim or lenograstim, during febrile neutropenia attack in hospitalized patients with solid tumors?en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
ozlem-uysal-sonmez.pdf
Boyut:
487.64 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/ Full text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu