Diyabetik retinopati gelişmemiş diyabetik olgularda retina, retina sinir lifi tabakası ve koroid kalınlığının değerlendirilmesi
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Amaç: Diyabetik retinopati gelişmemiş diyabetik olguların retina, retina sinir lifi tabakası (RSLT) ve koroid tabakası kalınlığının sağlıklı bireylerle karşılaştırılması.Gereç ve Yöntem: Çalışmaya 37-78 yaş arasında 133 diyabetik retinopati gelişmemiş diyabetik olgu ve 60 sağlıklı birey dahil edildi. Olguların Fourier prensibiyle çalışan optik koherens tomografi cihazı ile artırılmış derinlik görüntülemesi (enhanced depth imaging) modunda horizontal çizgisel taraması yapıldı. Alınan görüntülemelerde fovea merkezinden, fovea merkezine 1500 µm nazalden ve 1500 µm temporalden retina ve koroid kalınlıkları ölçümü yapıldı. Ayrıca cihazda yüklü bulunan RSLT kalınlığı ölçüm modu değerlerinde değişiklik yapılmaksızın RSLT kalınlığı ölçümü yapıldı.Bulgular: Çalışmaya dahil edilen DM grubunun yaş ortalaması 52.75±12.74 kontrol grubunun yaş ortalaması 53.83±5.95 idi. Göz içi basıncı (GİB) değerleri DM grubunda 16.26±2.90 mmHg ve kontrol grubunda 13.18±2.13 mmHg idi (p<0,001). Santral retina kalınlığı DM grubunda 226.24±18.78 µm, kontrol grubunda 216.37±14.79 µm idi (p<0.001). Subfoveal koroid kalınlığı DM grubunda 301.95±76.20 µm, kontrol grubunda 346.62±82.14 µm idi (p=0.001). RSLT kalınlığında ise gruplar arasında istatistiksel olarak anlamlı fark saptanmadı (p=0.494). Spearman testi ile korelasyon değerlendirmesinde diyabet varlığının artmış foveal retina kalınlığı, azalmış subfoveal koroid kalınlığı ve artmış GİB ile birliktelik gösterebileceği belirlendi (rho değer aralığı -0.262 ile 0.543, p<0.001).Sonuç: DM grubu sağlıklı bireylerle karşılaştırıldığında daha kalın retina, daha ince koroid kalınlığı ve daha yüksek GİB değerleri saptanmıştır. Gruplar arasında RSLT kalınlığı bakımından belirgin fark saptanmamıştır. Sonuçlarımız diyabetik retinopati gelişmemiş diyabetik olgularda GİB ve arka segment değerlendirilmesinin dikkatli yapılması gerektiğini göstermektedir
Purpose: Comparison of retinal, retinal nerve fiber layer (RNFL) and choroidal thicknesses in healthy subjects and diabetic patients without retinopathy.Materials and Methods: The study included 133 diabetic patients without diabetic retinopathy and 60 healthy subjects aging 37-78 years of age. Horizontal line scan of retina and choroid were performed using enhanced depth imaging mode of Fourier domain optical coherence tomography. The retinal and choroidal thicknesses were measured at the central fovea and at 1500 µm nasal and 1500 µm temporal from the center of the fovea. RNFL thickness measurements were performed using default RNFL thickness measurement mode provided by the device.Results: The mean age of diabetic group and control group were 52.75±12.74 and 53.83±5.95 years, respectively. Intraocular pressure (IOP) of diabetic group and control group were 16.26±2.90 and 13.18±2.13 mmHg, respectively (p<0.001). Central retinal thickness of diabetic group and control group were 226.24±18.78 and 216.37±14.79 µm, respectively (p<0.001). Subfoveal choroidal thickness of diabetic group and control group were 301.95±76.20 and 346.62±82.14 µm, respectively (p=0.001). We did not determine statistically significant difference between RNFL thicknesses of the groups (p=0.494). Correlation analysis using Spearman test revealed presence of diabetes showed association with increased foveal retinal thickness, decreased subfoveal choroidal thickness and increased IOP (range of rho values were -0.262 and 0.543, p<0.001).Conclusions: Diabetic group had higher retinal thickness, lower choroidal thickness and higher IOP values compared to healthy subjects. No significant RNFL thickness difference was determined between the groups. Results of the current study demonstrated that IOP and posterior segment of diabetic patients without retinopathy should be evaluated cautiously.
Purpose: Comparison of retinal, retinal nerve fiber layer (RNFL) and choroidal thicknesses in healthy subjects and diabetic patients without retinopathy.Materials and Methods: The study included 133 diabetic patients without diabetic retinopathy and 60 healthy subjects aging 37-78 years of age. Horizontal line scan of retina and choroid were performed using enhanced depth imaging mode of Fourier domain optical coherence tomography. The retinal and choroidal thicknesses were measured at the central fovea and at 1500 µm nasal and 1500 µm temporal from the center of the fovea. RNFL thickness measurements were performed using default RNFL thickness measurement mode provided by the device.Results: The mean age of diabetic group and control group were 52.75±12.74 and 53.83±5.95 years, respectively. Intraocular pressure (IOP) of diabetic group and control group were 16.26±2.90 and 13.18±2.13 mmHg, respectively (p<0.001). Central retinal thickness of diabetic group and control group were 226.24±18.78 and 216.37±14.79 µm, respectively (p<0.001). Subfoveal choroidal thickness of diabetic group and control group were 301.95±76.20 and 346.62±82.14 µm, respectively (p=0.001). We did not determine statistically significant difference between RNFL thicknesses of the groups (p=0.494). Correlation analysis using Spearman test revealed presence of diabetes showed association with increased foveal retinal thickness, decreased subfoveal choroidal thickness and increased IOP (range of rho values were -0.262 and 0.543, p<0.001).Conclusions: Diabetic group had higher retinal thickness, lower choroidal thickness and higher IOP values compared to healthy subjects. No significant RNFL thickness difference was determined between the groups. Results of the current study demonstrated that IOP and posterior segment of diabetic patients without retinopathy should be evaluated cautiously.
Açıklama
Anahtar Kelimeler
Diyabetes Mellitus, Göz İçi Basıncı, Koroid Kalınlığı, Retina Kalınlığı, Retina Sinir Lifi Tabakası Kalınlığı, Choroidal Thickness, Diabetes Mellitus, Intraocular Pressure, Retinal Nerve Fiber Layer Thickness, Retinal Thickness
Kaynak
Retina-Vitreus
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
23
Sayı
4
