Haemogram parameters in vitamin D deficiency
dc.authorid | 0000-0001-7306-5233 | en_US |
dc.authorid | 0000-0003-3085-7964 | |
dc.authorid | 0000-0002-3836-2125 | |
dc.contributor.author | Erkuş, Edip | |
dc.contributor.author | Aktaş, Gülali | |
dc.contributor.author | Atak, Burçin Meryem | |
dc.contributor.author | Koçak, Mehmet Zahid | |
dc.contributor.author | Duman, Tuba Taslamacıoğlu | |
dc.date.accessioned | 2021-06-23T19:49:29Z | |
dc.date.available | 2021-06-23T19:49:29Z | |
dc.date.issued | 2018 | |
dc.department | BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.description.abstract | Objective: To study haemogram derived inflammatory indices, mean platelet volume (MPV), red cell distribution width (RDW), and neutrophil to lymphocyte ratio (NLR) in vitamin D deficient patients and to compare to those subjects with normal vitamin D levels. Study Design: Descriptive study. Place and Duration of Study: Abant Izzet Baysal University Hospital, Bolu, Turkey, from March to May 2017. Methodology: Patients' data visiting the outpatient clinics of the institution was retrospectively obtained from patients' files and computerised database. Subjects were grouped into normal vitamin D and vitamin D deficiency groups, according to the serum Vitamin D levels. Seasonal threshold value for vitamin D in Bolu region was set as 10 ng/ml. General characteristics and laboratory data of the study population were recorded and compared. Results: Vitamin D deficiency was more common in subjects working inside as compared to those working outside (p=0.02), and in subjects with comorbidities compared to those without comorbidities (p= 0.31). Body mass index (BMI), MPV, NLR were significantly higher in vitamin D deficient group as compared to subjects with normal vitamin D levels. A MPV greater than 6.22 has 89% sensitivity and 55% specifity for vitamin D deficiency, and NLR greater than 1.69 has 76% sensitivity and 55% specifity for vitamin D deficiency. Conclusion: Elevated MPV and NLR may be the indicator of underlying serious vitamin D deficiency. Physicians should be alert and order a vitamin D assay in patients with elevated MPV or NLR, especially in endemic areas for vitamin D deficiency. | en_US |
dc.identifier.endpage | 782 | en_US |
dc.identifier.issn | 1022-386X | |
dc.identifier.issn | 1681-7168 | |
dc.identifier.issue | 10 | en_US |
dc.identifier.pmid | 30266124 | en_US |
dc.identifier.startpage | 779 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12491/9519 | |
dc.identifier.uri | https://www.webofscience.com/wos/woscc/full-record/WOS:000445920300013 | |
dc.identifier.volume | 28 | en_US |
dc.identifier.wos | WOS:000445920300013 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Erkuş, Edip | |
dc.institutionauthor | Aktaş, Gülali | |
dc.institutionauthor | Atak, Burçin Meryem | |
dc.institutionauthor | Koçak, Mehmet Zahid | |
dc.institutionauthor | Duman, Tuba Taslamacıoğlu | |
dc.language.iso | en | en_US |
dc.publisher | Coll Physicians & Surgeons Pakistan | en_US |
dc.relation.ispartof | Jcpsp-Journal Of The College Of Physicians And Surgeons Pakistan | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Mean Platelet Volume | en_US |
dc.subject | Neutrophil to Lymphocyte Ratio | en_US |
dc.subject | Inflammation | en_US |
dc.subject | Vitamin D | en_US |
dc.title | Haemogram parameters in vitamin D deficiency | en_US |
dc.type | Article | en_US |
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