Haemogram parameters in vitamin D deficiency

dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-3085-7964
dc.authorid0000-0002-3836-2125
dc.contributor.authorErkuş, Edip
dc.contributor.authorAktaş, Gülali
dc.contributor.authorAtak, Burçin Meryem
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.date.accessioned2021-06-23T19:49:29Z
dc.date.available2021-06-23T19:49:29Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To study haemogram derived inflammatory indices, mean platelet volume (MPV), red cell distribution width (RDW), and neutrophil to lymphocyte ratio (NLR) in vitamin D deficient patients and to compare to those subjects with normal vitamin D levels. Study Design: Descriptive study. Place and Duration of Study: Abant Izzet Baysal University Hospital, Bolu, Turkey, from March to May 2017. Methodology: Patients' data visiting the outpatient clinics of the institution was retrospectively obtained from patients' files and computerised database. Subjects were grouped into normal vitamin D and vitamin D deficiency groups, according to the serum Vitamin D levels. Seasonal threshold value for vitamin D in Bolu region was set as 10 ng/ml. General characteristics and laboratory data of the study population were recorded and compared. Results: Vitamin D deficiency was more common in subjects working inside as compared to those working outside (p=0.02), and in subjects with comorbidities compared to those without comorbidities (p= 0.31). Body mass index (BMI), MPV, NLR were significantly higher in vitamin D deficient group as compared to subjects with normal vitamin D levels. A MPV greater than 6.22 has 89% sensitivity and 55% specifity for vitamin D deficiency, and NLR greater than 1.69 has 76% sensitivity and 55% specifity for vitamin D deficiency. Conclusion: Elevated MPV and NLR may be the indicator of underlying serious vitamin D deficiency. Physicians should be alert and order a vitamin D assay in patients with elevated MPV or NLR, especially in endemic areas for vitamin D deficiency.en_US
dc.identifier.endpage782en_US
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue10en_US
dc.identifier.pmid30266124en_US
dc.identifier.startpage779en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9519
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000445920300013
dc.identifier.volume28en_US
dc.identifier.wosWOS:000445920300013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorErkuş, Edip
dc.institutionauthorAktaş, Gülali
dc.institutionauthorAtak, Burçin Meryem
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.language.isoenen_US
dc.publisherColl Physicians & Surgeons Pakistanen_US
dc.relation.ispartofJcpsp-Journal Of The College Of Physicians And Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.subjectInflammationen_US
dc.subjectVitamin Den_US
dc.titleHaemogram parameters in vitamin D deficiencyen_US
dc.typeArticleen_US

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