The Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties

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dc.contributor.authorKaya, Gul
dc.contributor.authorKoc, Eda Ondul
dc.contributor.authorOzdemir, Sadin
dc.contributor.authorYalcin, M. Serkan
dc.contributor.authorOcakoglu, Kasim
dc.contributor.authorDizge, Nadir
dc.date.accessioned2024-09-25T19:57:35Z
dc.date.available2024-09-25T19:57:35Z
dc.date.issued2024
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractChromium aluminum carbide (Cr2AlC) MAX phase and Cr2CTx (MXene-Cr) were synthesized by the pressureless sintering method and hydrothermal method, respectively. In addition to this, the free radical scavenging activities (FRSA) of MAX-Cr phase and MXene-Cr compounds were tested and compared with ascorbic acid and trolox as standard compounds. The obtained FRSA results of MAX-Cr phase and MXene-Cr were 42.82 and 59.64%, respectively, at 100 mg/L concentration. MXene-Cr showed a 66.90% inhibitory effect on alpha-amylase at 200 mg/L. The DNA nuclease activity of compounds was determined to be extremely satisfactory at 50, 100, and 200 mg/L concentrations. Moreover, the prepared MAX-Cr phase and MXene-Cr were investigated for antimicrobial activity against six bacterial and two fungal strains by the broth microdilution method. Compounds provided more significant inhibition against Gram-positive bacteria than Gram-negative bacteria and fungi. MAX-Cr phase and MXene-Cr almost completely inhibited microbial cell viability at a 25 mg/L concentration. Additionally, MXene-Cr showed 89.86% and 87.01% antibiofilm activity against S. aureus and P. aeruginosa, respectively, while the antibiofilm activity of the MAX-Cr phase was over 90%.en_US
dc.identifier.doi10.1007/s12010-024-04910-w
dc.identifier.issn0273-2289
dc.identifier.issn1559-0291
dc.identifier.pmid38538871en_US
dc.identifier.scopus2-s2.0-85188820827en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s12010-024-04910-w
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13471
dc.identifier.wosWOS:001194763400002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofApplied Biochemistry And Biotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectCr2AlC MAX phase (MAX-Cr)en_US
dc.subjectCr2CTx (MXene-Cr)en_US
dc.subjectAntioxidanten_US
dc.subjectAntimicrobialen_US
dc.subjectDNA cleavageen_US
dc.subjectBiofilm inhibitionen_US
dc.titleThe Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Propertiesen_US
dc.typeArticleen_US

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