Assessment of multiple areas on magnetic resonance midsagittal brain images in multiple sclerosis patients

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dc.authorid0000-0002-0334-1658
dc.authorid0000-0001-8616-832X
dc.contributor.authorKosif, Rengin
dc.contributor.authorTürkoğlu, Şule Aydın
dc.contributor.authorBolaç, Elif Sultan
dc.contributor.authorDağıstan, Emine
dc.date.accessioned2021-06-23T18:51:38Z
dc.date.available2021-06-23T18:51:38Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of the study was to compare the first and last magnetic resonance images (MRIs) in patients diagnosed with multiple sclerosis (MS) with MRIs of normal subjects. We wanted to investigate the region initially involved in MS patients. In this retrospective study, midsagittal plane was explored on brain MRIs taken at the time when MS diagnosis was established and the last MRI was obtained following treatment for MS. Comparison was done between healthy subjects and patients diagnosed with MS. The measures included the area of corpus callosum, cerebrum, cerebellum, pons, bulbus, fourth ventricle and pituitary gland. As a result, while there was growth in the fourth ventricle area, there was shrinkage in the other areas in MS patients. In women, the tissues involved at the beginning of the disease were pituitary gland, cerebrum and bulbus, and in men corpus callosum and cerebrum. Atrophy was not time-dependent. Assessment of the correlation between the Expanded Disability Status Scale (EDDS) and atrophy revealed an increase in EDDS (disease progression) to be associated with a decrease in the area of cerebrum and corpus callosum in men, and an increase in the fourth ventricular area in women. In conclusion, we demonstrated that pituitary gland atrophy develops in the early stage of MS, especially in women. Additional studies are needed to investigate the phenomenon of early pituitary and bulbus atrophy in women versus late atrophy of these tissues in men. © 2017, Academy of Medical Sciences of Croatica. All rights reserved.en_US
dc.identifier.endpage24en_US
dc.identifier.issn1330-0164
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85069298968en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3918
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85069298968&partnerID=40&md5=0cfe2da44f7f5434c50f66a288c5f9ed
dc.identifier.volume71en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKosif, Rengin
dc.institutionauthorTürkoğlu, Şule Aydın
dc.institutionauthorBolaç, Elif Sultan
dc.institutionauthorDağıstan, Emine
dc.language.isoenen_US
dc.publisherAcademy of Medical Sciences of Croaticaen_US
dc.relation.ispartofActa Medica Croaticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAssessmenten_US
dc.subjectBrainen_US
dc.subjectMidsagittal areasen_US
dc.subjectMultiple sclerosisen_US
dc.titleAssessment of multiple areas on magnetic resonance midsagittal brain images in multiple sclerosis patientsen_US
dc.title.alternativeOcjena mnogostrukih podru?ja na srednjesagitalnim slikama magnetske rezonancije mozga u bolesnika s multiplom sklerozomen_US
dc.typeArticleen_US

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