Genetic studies of bipolar disorder: A Review

Basit Öğe Kaydı
dc.authorid0000-0002-1422-1600
dc.contributor.authorArısoy, Özden
dc.contributor.authorOral, E. Timuçin
dc.date.accessioned2021-06-23T18:52:11Z
dc.date.available2021-06-23T18:52:11Z
dc.date.issued2009
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBipolar disorder is a severe mental illness that afflicts approximately 1% of the world's population, and is characterized by mood swings from elation to depression. Although the etiology of bipolar disorder remains unclear, heritable factors have been shown to be involved. Family, twin, and adoption studies suggest a genetic etiology. Molecular genetic studies also support a genetic component. Many chromosomal regions have been implicated by these molecular genetic studies, but no single susceptibility gene has been identified. These findings show that bipolar disorder has a complex genetic etiology in which multiple unidentified genes and environmental factors play an important role in its pathogenesis. Herein, molecular genetic studies of bipolar disorder are reviewed based on a search of Medline using the key words, bipolar, genetic, and chromosome. Studies with positive results for bipolar disorder were selected first. The findings from these molecular genetic studies are reviewed systematically, chromosome by chromosome. Causes of the differences between the reported findings and of non-replication are discussed. Finally, important factors for designing a genetic study of bipolar disorder are examined.en_US
dc.identifier.endpage12en_US
dc.identifier.issn1300-2163
dc.identifier.issue3en_US
dc.identifier.pmid19757227en_US
dc.identifier.scopus2-s2.0-77749297969en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4159
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-77749297969&partnerID=40&md5=20c5ca0b7ac576e9d497f8bf2151d5ef
dc.identifier.volume20en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorArısoy, Özden
dc.language.isoenen_US
dc.publisherTurkish Association of Nervous and Mental Healthen_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAssociationen_US
dc.subjectBipolaren_US
dc.subjectChromosomeen_US
dc.subjectGeneticen_US
dc.subjectLinkageen_US
dc.titleGenetic studies of bipolar disorder: A Reviewen_US
dc.typeReview Articleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
ozden-arisoy.pdf
Boyut:
192.8 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/ Full text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu