Intrathecal sufentanil (1.5?g) added to hyperbaric bupivacaine (0.5%) for elective cesarean section provides adequate analgesia without need for pruritus therapy

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dc.authorid0000-0003-0811-4945
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorÖzdemir, İsmail
dc.contributor.authorKocaman, Buket
dc.contributor.authorYücel, Oğuz
dc.date.accessioned2021-06-23T18:54:14Z
dc.date.available2021-06-23T18:54:14Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: We compared the effects of different doses of intrathecal sufentanil when administered together with hyperbaric bupivacaine for elective caesarean section. Methods: This was a prospective, randomized, double-blind, controlled trial involving 100 pregnant women, American Society of Anesthesiologists (ASA) I-II, who were scheduled for elective caesarean section under spinal anesthesia. The patients were assigned to four groups according to the dose of sufentanil used: no sufentanil (group I; placebo) or 1.5, 2.5, or 5.0?g sufentanil (groups 2-4, respectively). In every group, the local anesthetic used was hyperbaric bupivacaine 0.5% (12.5 mg), and the total volume of the solution was 3.5 ml. The duration of complete analgesia, maternal side effects, and maternal/ fetal outcomes were recorded. The duration of complete analgesia was defined as the time from intrathecal injection to a vernal analogue score (VAS) of more than 0. Results: No patient experienced intraoperative pain. The duration of complete analgesia was prolonged in all groups receiving opioids. The duration of the analgesia and the 0- to 6-h intravenous analgesic requirements were similar in the sufentanil groups. Moreover, the sufentanil groups had longer durations of complete analgesia than the placebo group. Pruritus was more frequent in the 2.5- and 5-?g sufentanil groups than in the 1.5-?g sufentanil and placebo groups. There were no differences among the groups in umbilical cord blood gases on in neonatal Apgar scores. Conclusion: The addition of sufentanil 1.5 and 2.5?g to hyperbaric bupivacaine provided adequate anesthesia for caesarean delivery and good postoperative analgesia. In addition, the incidence of pruritus was significantly lower in the 1.5-?g sufentanil group when compared with that in the 2.5- and 5-?g groups. © JSA 2006.en_US
dc.identifier.doi10.1007/s00540-006-0437-2
dc.identifier.endpage278en_US
dc.identifier.issn0913-8668
dc.identifier.issue4en_US
dc.identifier.pmid17072691en_US
dc.identifier.scopus2-s2.0-33750455424en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage274en_US
dc.identifier.urihttps://doi.org/10.1007/s00540-006-0437-2
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4322
dc.identifier.volume20en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzdemir, İsmail
dc.institutionauthorYücel, Oğuz
dc.language.isoenen_US
dc.relation.ispartofJournal of Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCesarean sectionen_US
dc.subjectIntrathecalen_US
dc.subjectPruritusen_US
dc.subjectSufentanilen_US
dc.titleIntrathecal sufentanil (1.5?g) added to hyperbaric bupivacaine (0.5%) for elective cesarean section provides adequate analgesia without need for pruritus therapyen_US
dc.typeArticleen_US

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