Synthesis and crystal structure of new heterocyles derived from saccharin and uracil carrying 1,2,4-oxadiazolylmethyl group

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dc.authorid0000-0002-0873-694Xen_US
dc.authorid0000-0002-8658-3897en_US
dc.contributor.authorDürüst, Yaşar
dc.contributor.authorÖzer, Besra
dc.contributor.authorCariuki, Benson M.
dc.date.accessioned2021-06-23T19:42:08Z
dc.date.available2021-06-23T19:42:08Z
dc.date.issued2015
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.description.abstractSaccharin, uracil, and 1,2,4-oxadiazole heterocyles are important in terms of exhibiting various biological acitivities. In this work, four series of 1,2,4-oxadiazolylmethyl-substituted saccharin, and uracil derivatives are synthesized and their structures are identified by means of spectral/physical characteristics. The first series are oxadiazolylmethyl-substituted saccharins. The second one is oxadiazole-substituted uracils which are obtained as a separable mixture of both mono- and bis-substituted end products. Third series is obtained from 5-amino uracil and chloromethyl oxadiazoles. The fourth group is oxadiazolyl methyl-substituted imino uracils. The structures of some title compounds are also confirmed by X-ray diffraction data. [GRAPHICS] .en_US
dc.identifier.doi10.1007/s11030-015-9577-3
dc.identifier.endpage230en_US
dc.identifier.issn1381-1991
dc.identifier.issn1573-501X
dc.identifier.issue2en_US
dc.identifier.pmid25754077en_US
dc.identifier.scopus2-s2.0-84939946945en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage213en_US
dc.identifier.urihttps://doi.org/10.1007/s11030-015-9577-3
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8356
dc.identifier.volume19en_US
dc.identifier.wosWOS:000352822100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDürüst, Yaşar
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofMolecular Diversityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSaccharinen_US
dc.subjectUracilen_US
dc.subject1,2,4-Oxadiazoleen_US
dc.subjectN-substitutionen_US
dc.subjectX-ray Diffractionen_US
dc.titleSynthesis and crystal structure of new heterocyles derived from saccharin and uracil carrying 1,2,4-oxadiazolylmethyl groupen_US
dc.typeArticleen_US

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