Effect of pregabalin and dexamethasone on postoperative analgesia after septoplasty

Basit Öğe Kaydı
dc.authorid0000-0002-2311-6431
dc.authorid0000-0002-0363-9307
dc.authorid0000-0001-7476-2217
dc.authorid0000-0002-1630-2033
dc.authorid0000-0002-4229-6589
dc.authorid0000-0002-6223-4254
dc.authorid0000-0002-9001-2309
dc.authorid0000-0003-0009-8952
dc.contributor.authorDemirhan, Abdullah
dc.contributor.authorAkkaya, Akcan
dc.contributor.authorTekelioğlu, Ümit Yaşar
dc.contributor.authorApuhan, Tayfun
dc.contributor.authorBilgi, Murat
dc.contributor.authorYurttaş, Veysel
dc.contributor.authorBayır, Hakan
dc.contributor.authorYıldız, İsa
dc.contributor.authorGök, Üzeyir
dc.contributor.authorKoçoğlu, Hasan
dc.date.accessioned2021-06-23T18:55:22Z
dc.date.available2021-06-23T18:55:22Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives. The aim of this study was to explore effect of a combination of pregabalin and dexamethasone on pain control after septoplasty operations. Methods. In this study, 90 patients who were scheduled for septoplasty under general anesthesia were randomly assigned into groups that received either placebo (Group C), pregabalin (Group P), or pregabalin and dexamethasone (Group PD). Preoperatively, patients received either pregabalin 300 mg one hour before surgery, dexamethasone 8 mg intravenously during induction, or placebo according to their allocation. Postoperative pain treatment included tramadol and diclofenac sodium 30 minutes before the end of the operation. Numeric rating scale (NRS) for pain assessment, side effects, and consumption of tramadol, pethidine, and ondansetron were recorded. Results. The median NRS score at the postoperative 0 and the 2nd h was significantly higher in Group C than in Group P and Group PD (P?0.004 for both). The 24 h tramadol and pethidine, consumptions were significantly reduced in Groups P and PD compared to Group C (P<0.001 and P<0.001). The incidence of blurred vision was significantly higher in Group PD compared to Group C within both 0-2 h and 0-24 h periods (P=0.002 and P<0.001, resp.). Conclusions. We conclude that administration of 300 mg pregabalin preoperatively may be an adequate choice for pain control after septoplasty. Addition of dexamethasone does not significantly reduce pain in these patients.en_US
dc.identifier.doi10.1155/2014/850794
dc.identifier.issn2090-1542
dc.identifier.scopus2-s2.0-84901272817en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1155/2014/850794
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4752
dc.identifier.volume2014en_US
dc.identifier.wosWOS:000215764400027en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorAkkaya, Akcan
dc.institutionauthorTekelioğlu, Ümit Yaşar
dc.institutionauthorApuhan, Tayfun
dc.institutionauthorBilgi, Murat
dc.institutionauthorYurttaş, Veysel
dc.institutionauthorBayır, Hakan
dc.institutionauthorYıldız, İsa
dc.institutionauthorGök, Üzeyir
dc.institutionauthorKoçoğlu, Hasan
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.ispartofPain Research and Treatmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDexamethasoneen_US
dc.subjectPregabalin
dc.subjectSeptoplasty
dc.subjectPostoperative
dc.titleEffect of pregabalin and dexamethasone on postoperative analgesia after septoplastyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
abdullah-demirhan.pdf
Boyut:
1.26 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/ Full text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Cerrahi Tıp Bilimleri Bölümü Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu