The Relationship Between Serum Pentraxine 3 Levels and Hematological Markers in Patients With Rheumatoid Arthritis

Basit Öğe Kaydı
dc.contributor.authorSağ, Mustafa Serdar
dc.contributor.authorSağ, Sinem
dc.contributor.authorTekeoğlu, İbrahim
dc.contributor.authorKamanlı, Ayhan
dc.contributor.authorNas, Kemal
dc.contributor.authorHarman, Halil
dc.date.accessioned2021-06-23T18:24:56Z
dc.date.available2021-06-23T18:24:56Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: This study aims to investigate the association of pentraxin 3 (PTX3) with neutrophil/lymphocyte ratio (NLR) rather than the disease activity score 28 using C-reactive protein in rheumatoid arthritis (RA). Patients and methods: The study included 59 RA patients (11 males, 48 females; mean age 53.79±13.55 years; range 40 to 66 years) and 20 healthy controls (5 males, 15 females; mean age 50.41±6.11 years; range 43 to 56 years). Complete blood count tests were recorded and NLR and platelet/lymphocyte ratio were calculated. PTX3 and interleukin-6 levels were examined in serum samples. Disease activity of RA patients was assessed by disease activity score 28. Results: Demographic characteristics were similar between the two groups, with no statistically significant difference in terms of sex, age, and body mass index (p>0.05). NLR, PTX3 and interleukin-6 levels were higher in patients with RA than the control group (p<0.05). While erythrocyte sedimentation rate had a positive correlation with mean platelet volume, we found no correlation between NLR and other parameters of disease activity, PTX3, and interleukin-6. Conclusion: We found no correlation between PTX3 and disease activity score 28 or NLR, although PTX3 levels were higher in RA patients than the controls. As a result, we were unable to establish a relationship between PTX3 and disease activity, directly or indirectly. To our knowledge, our study was the first to investigate the relationship between PTX3 and NLR.en_US
dc.identifier.doi10.5606/ArchRheumatol.2018.6394
dc.identifier.endpage44en_US
dc.identifier.issn2148-5046
dc.identifier.issn2618-6500
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85042860977en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage39en_US
dc.identifier.trdizinid289977en_US
dc.identifier.urihttps://doi.org/10.5606/ArchRheumatol.2018.6394
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpnNU9UYzNOdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/1034
dc.identifier.volume33en_US
dc.identifier.wosWOS:000429930000005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorHarman, Halil
dc.language.isoenen_US
dc.relation.ispartofArchives of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRomatolojien_US
dc.titleThe Relationship Between Serum Pentraxine 3 Levels and Hematological Markers in Patients With Rheumatoid Arthritisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu