Evaluation of the protective effect of the cup therapy on the epileptic seizure in rats

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dc.authorid0000-0002-8212-7149en_US
dc.authorid0000-0001-9034-6379en_US
dc.authorid0000-0002-0305-5758en_US
dc.contributor.authorÇetinkaya, Ayhan
dc.contributor.authorKaramaden, Esra Fidan
dc.contributor.authorGöksu, Selim
dc.contributor.authorBozat, Bihter Gökçe
dc.contributor.authorDemir, Şerif
dc.date.accessioned2023-07-17T12:00:29Z
dc.date.available2023-07-17T12:00:29Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Cup therapy has an important place in traditional and complementary medicine applications. The purpose of our study, this is the first time to investigate the protective effect of cup therapy in rats on experimentally generated epileptic seizures in new rat modeling created by different anatomic regions. Methods: A total of 42 Wistar albino rats were randomly divided into 6 groups (n:7). The "new dry cup" was applied to the G1 group, and the "new wet cup" model was applied to the G2. In the G3 group, an "epilepsy model" (PTZ, 35 mg / kg) was created and "diazepam" (2.5 mg / kg) was given to G4. "Dry cup" and "wet cup" models were applied to the G5 and G6 groups, respectively. 24 hours after the cupping therapies, the rats were injected with PTZ and the epilepsy behavior scores of the rats in all groups were recorded for 20-30 minutes. Results: In the 'Open Area' and 'Elevated Plus Maze' tests, there was no behavioral difference between the cup therapy group and the control group (p > 0.05). Given all the parameters, the G4 group significantly reduces the seizure compared to other groups (p < 0.05). There is a significant difference in G2, G5 and G6 groups compared to G3 in the phases parameter (p < 0.05). Conclusions: In this study, the new wet cup therapy (G2), which was applied for the first time, had a protective effect on seizures. G2, G5 and G6 groups are observed to suppress seizures compared to G3. Our findings are expected to contribute greatly to animal model analysis in the future.en_US
dc.identifier.citationCetinkaya, A., FİDAN, E., GÖKSU, S., BOZAT, B., & Demir, S. (2021). Evaluation of the Protective Effect of The Cup Therapy on the Epileptic Seizure in Rats. Konuralp Medical Journal, 13(3), 606-613.en_US
dc.identifier.doi10.18521/ktd.777484
dc.identifier.endpage613en_US
dc.identifier.issn1309-3878
dc.identifier.issue3en_US
dc.identifier.startpage606en_US
dc.identifier.trdizinid479666en_US
dc.identifier.urihttp://dx.doi.org/10.18521/ktd.777484
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11299
dc.identifier.volume13en_US
dc.identifier.wosWOS:000709040200018en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÇetinkaya, Ayhan
dc.institutionauthorGöksu, Selim
dc.institutionauthorBozat, Bihter Gökçe
dc.language.isoenen_US
dc.publisherDüzce Univ, Fac Medicineen_US
dc.relation.ispartofKonuralp Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpilepsyen_US
dc.subjectSeizureen_US
dc.subjectCup Therapyen_US
dc.subjectWet Cupping Therapyen_US
dc.subjectMedicineen_US
dc.subjectPainen_US
dc.titleEvaluation of the protective effect of the cup therapy on the epileptic seizure in ratsen_US
dc.typeArticleen_US

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