Microscopic examination of placenta of rats prenatally exposed to aloe barbadensis: a preliminary study

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dc.authorid0000-0002-0334-1658
dc.authorid0000-0002-3669-6631
dc.contributor.authorKosif, Rengin
dc.contributor.authorAkta, Gülhan
dc.contributor.authorÖztekin, Aynure
dc.date.accessioned2021-06-23T19:25:49Z
dc.date.available2021-06-23T19:25:49Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAloe barbadensis is the most widely used both commercially and therapeutic properties. It has been used for an array of ailments since ancient times as a medicinal plant. There are more than 360 different species of Aloe. Its products have been used in health foods for medical and preservative purposes. The objective of this study was to search the effects of Aloe barbadensis on the rat's placenta. Gel form of Aloe barbadensis is used in the study. It is commercial, preserved but otherwise untreated form of Aloe Barbadensis gel capsul. Female Wistar Albino rats were divided into three groups. Placenta specimens from each groups were processed for the microscopic examination. Trophoblastic giant cells and spongiotrophoblasts were decreased in number after Aloe barbadensis; trophoblastic giant cells which showed degenerative changes. The nuclei of these giant cells were going degeneration characterized by pyknosis and bizarrely shaped. Extracellular matrix production around the cells was increased, thicker and more irregular basal membrane like formation around the cells. Decreased and abnormal vessel formation in labyrinth area was clear and reduced functional capacity of the trophoblastic barier. The study shows that, in the presence of Aloe barbadensis, relevant alterations associated with a possible compensatory adjustment to maintain adequate metabolic exchange take place in the structure of placenta. Our results also demonstrated that the exposure to Aloe barbadensis during pregnancy not led to fetal growth retardation, fetal death, abortion or teratogenic effect.en_US
dc.identifier.endpage281en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-56849132301en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage275en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6264
dc.identifier.urihttps://scielo.conicyt.cl/scielo.php?script=sci_abstract&pid=S0717-95022008000200005&lng=en&nrm=iso
dc.identifier.volume26en_US
dc.identifier.wosWOS:000261809200005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKosif, Rengin
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal Of Morphologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAloe Barbadensisen_US
dc.subjectEffecten_US
dc.subjectPlacentaen_US
dc.subjectMicroscopic Examinationen_US
dc.titleMicroscopic examination of placenta of rats prenatally exposed to aloe barbadensis: a preliminary studyen_US
dc.typeArticleen_US

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