Assessment of health related quality of life in chronic hepatitis B infection patients in Turkey: a multicenter study

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dc.authorid0000-0001-6645-6527
dc.authorid0000-0002-3021-8831
dc.authorid0000-0003-0442-5981
dc.contributor.authorKaracaer, Zehra
dc.contributor.authorÇakır, Banu
dc.contributor.authorErdem, Hakan
dc.contributor.authorUğurlu, Kenan
dc.contributor.authorDurmuş, Gül
dc.contributor.authorSırmatel, Fatma
dc.date.accessioned2021-06-23T19:44:01Z
dc.date.available2021-06-23T19:44:01Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionEASL International Liver Congress -- APR 13-17, 2016 -- Barcelona, SPAINen_US
dc.description.abstractQuality of Life (HBQOL) questionnaire form. Because five-factor structure for the HBQOL fitted well into Turkish data in publised study, Transmissibility subscale was not analyzed. The data analyzed via SPSS v.22.0 (SPSS Inc., Chicago, IL, USA). The factors related to HRQOL were determined. p < 0.05 was considered significant. Results: A total of 4257 patients (1529 patients in group 1, 1721 patients in group 2, 1007 patients in group 3) were studied. The study group included 2559 (60.1%) male and 1698 (%39.9) female with a median age of 40 years (min-max: 18–84 years). The median ALT levels was 25 U/L (min-max: 0–961 U/L), and the median HBV DNA levels was 76 IU/mL (0–19 × 109 IU/mL). 3657 (85.9%) cases were HbeAg negative. There were statistically significant differences among the study groups according to SF-36 physical component scores, mental component scores and HBQOL total scores (respectively p = <0.001, p = <0.001, p = <0.001). The statistically significant differences were found between SF-36 physical component scores and education level ( p = 0.028), undergoing antiviral treatment ( p = <0.001), ALT levels ( p = 0.004); also SF-36 mental component scores and undergoing antiviral treatment ( p = 0.012), ALT levels ( p = 0.038). Statistically significant differences were noted regarding HBQOL total scores and gender ( p = 0.001), marriage status ( p = 0.002), undergoing antiviral treatment ( p = 0.011), other chronic disease status ( p = <0.001), hospital type ( p = <0.001), HBeAg status ( p = <0.001), ALT levels ( p = 0.001). When all these factors were controlled simultaneously, the scores were higher significantly in inactive CHB patients.en_US
dc.description.sponsorshipEASLen_US
dc.identifier.doi10.1016/S0168-8278(16)00587-0
dc.identifier.endpageS384en_US
dc.identifier.issn0168-8278
dc.identifier.issn1600-0641
dc.identifier.startpageS383en_US
dc.identifier.urihttps://doi.org/10.1016/S0168-8278(16)00587-0
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8900
dc.identifier.volume64en_US
dc.identifier.wosWOS:000398711700582en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorSırmatel, Fatma
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal Of Hepatologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSF-36en_US
dc.subjectHbeAg Negative
dc.subjectChronic Hepatitis B
dc.titleAssessment of health related quality of life in chronic hepatitis B infection patients in Turkey: a multicenter studyen_US
dc.typeConference Objecten_US

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