Assessment of health related quality of life in chronic hepatitis B infection patients in Turkey: a multicenter study
Yükleniyor...
Dosyalar
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Quality of Life (HBQOL) questionnaire form. Because five-factor structure for the HBQOL fitted well into Turkish data in publised study, Transmissibility subscale was not analyzed. The data analyzed
via SPSS v.22.0 (SPSS Inc., Chicago, IL, USA). The factors related to HRQOL were determined. p < 0.05 was considered significant. Results: A total of 4257 patients (1529 patients in group 1, 1721 patients in group 2, 1007 patients in group 3) were studied. The study group included 2559 (60.1%) male and 1698 (%39.9) female with a median age of 40 years (min-max: 18–84 years). The median ALT levels was 25 U/L (min-max: 0–961 U/L), and the median HBV DNA
levels was 76 IU/mL (0–19 × 109 IU/mL). 3657 (85.9%) cases were HbeAg negative. There were statistically significant differences among the study groups according to SF-36 physical component
scores, mental component scores and HBQOL total scores (respectively p = <0.001, p = <0.001, p = <0.001). The statistically significant differences were found between SF-36 physical component scores and education level ( p = 0.028), undergoing antiviral treatment ( p = <0.001), ALT levels ( p = 0.004); also SF-36 mental component scores and undergoing antiviral treatment ( p = 0.012), ALT levels ( p = 0.038). Statistically significant differences were noted regarding HBQOL total scores and gender ( p = 0.001), marriage status ( p = 0.002), undergoing antiviral treatment ( p = 0.011), other chronic disease status ( p = <0.001), hospital type ( p = <0.001), HBeAg status ( p = <0.001), ALT levels ( p = 0.001). When all these factors were controlled simultaneously, the scores were higher significantly in
inactive CHB patients.
Açıklama
EASL International Liver Congress -- APR 13-17, 2016 -- Barcelona, SPAIN
Anahtar Kelimeler
SF-36, HbeAg Negative, Chronic Hepatitis B
Kaynak
Journal Of Hepatology
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
64
