Evaluation of antibacterial, antitumor, antioxidant activities and phenolic constituents of field-grown and in vitro-grown Lysimachia vulgaris L.

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dc.authorid0000-0001-7712-2813
dc.authorid0000-0001-5245-6294
dc.authorid0000-0001-9617-6673
dc.contributor.authorYıldırım, Arzu
dc.contributor.authorGüner, Birgül
dc.contributor.authorPehlivan Karakaş, Fatma
dc.contributor.authorTürker, Arzu
dc.date.accessioned2021-06-23T18:51:39Z
dc.date.available2021-06-23T18:51:39Z
dc.date.issued2017
dc.departmentBAİBÜ, Ziraat Fakültesi, Tarla Bitkileri Bölümüen_US
dc.description.abstractBACKGROUND: Lysimachia vulgaris L. (Yellow loosestrife) is a medicinal plant in the family Myrsinaceae. It has been used in the treatment of fever, ulcer, diarrhea and wounds in folk medicine. It has also analgesic, expectorant, astringent and anti-inflammatory activities. Two different sources of the plant (field-grown and in vitro-grown) were used to evaluate the biological activities (antibacterial, antitumor and antioxidant) of L. vulgaris. In vitro-grown plant materials were collected from L. vulgaris plants that were previously regenerated in our laboratory.MATERIALS AND METHODS: Plant materials were extracted with water, ethanol and acetone. For antibacterial test, disc diffusion method and 10 different pathogenic bacteria were used. Antioxidant activity was indicated by using DPPH method. The total phenol amount by using Folin-Ciocaltaeu method and the total flavonoid amount by using aluminum chloride (AlCl3) colorimetric method were determined.RESULTS: Generally, yellow loosestrife extracts demonstrated antibacterial activity against Gram-positive bacteria (Staphylococcus aureus, S. epidermidis and Streptococcus pyogenes). Strong antitumor activity of yellow loosestrife was observed via potato disc diffusion bioassay. Nine different phenolics were also determined and compared by using High-Performance Liquid Chromatography (HPLC).CONCLUSION: Future investigations should be focused on fractionation of the extracts to identify active components for biological activity.en_US
dc.identifier.doi10.21010/ajtcam.v14i2.19
dc.identifier.endpage187en_US
dc.identifier.issn2505-0044
dc.identifier.issue2en_US
dc.identifier.pmid28573234en_US
dc.identifier.scopus2-s2.0-85027516576en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage177en_US
dc.identifier.urihttps://doi.org/10.21010/ajtcam.v14i2.19
dc.identifier.urihttps://hdl.handle.net/20.500.12491/3925
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85027516576&doi=10.21010%2fajtcam.v14i2.19&partnerID=40&md5=752c7009312e61dffcff234ec9da1552
dc.identifier.volume14en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldırım, Arzu
dc.institutionauthorGüner, Birgül
dc.institutionauthorPehlivan Karakaş, Fatma
dc.language.isoenen_US
dc.relation.ispartofAfrican journal of traditional, complementary, and alternative medicines : AJTCAMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAluminum chloride colorimetricen_US
dc.subjectantibacterialen_US
dc.subjectantitumoren_US
dc.subjectDPPHen_US
dc.subjectFolin-Ciocalteauen_US
dc.subjectHPLCen_US
dc.subjectLysimachia vulgarisen_US
dc.titleEvaluation of antibacterial, antitumor, antioxidant activities and phenolic constituents of field-grown and in vitro-grown Lysimachia vulgaris L.en_US
dc.typeArticleen_US

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