Assessment of neutrophil-lymphocyte and platelet-lymphocyte ratios in ankylosing spondylitis
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Dosyalar
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish League Against Rheumatism
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We read the article published by Erkol İnal et al.1 with great interest. The authors evaluated the associations between neutrophil-lymphocyte ratio (NLR), mean platelet volume, and plateletlymphocyte ratio (PLR) along with disease activity in ankylosing spondylitis. They found that mean platelet volume is not associated with disease activity, whereas NLR and PLR may reflect disease activity. Although this is a
well-written study, it has some methodological
drawbacks. The researchers screened complete blood counts, erythrocyte sedimentation rate, C-reactive protein, disease activity, clinical status, and
functional status of ankylosing spondylitis patients. They expressed inclusion and exclusion criteria. However, exclusion criteria of this study did not conform with those as noted in other studies.2,3 They did not question the factors such as metabolic syndrome, anemia, secondary hyperparathyroidism, impaired thyroid function, chronic obstructive pulmonary disease, obstructive sleep apnea, connective tissue disease, allergic rhinitis, asthma and smoking history in the patient and control groups. These factors can affect NLR and PLR values. All these elements should be taken into account for determining exclusion criteria. Otherwise, incorrect findings may be obtained when the results are interpreted.
Açıklama
Anahtar Kelimeler
Neutrophil, Lymphocyte, Platelet-Lymphocyte, Ankylosing Spondylitis
Kaynak
Archives Of Rheumatology
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
31
Sayı
2