Effect of tube filling order on specific coagulation parameters in healthy subjects

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dc.authorid0000-0002-4060-3354en_US
dc.contributor.authorSerin, Erdinç
dc.contributor.authorBuğdaycı, Güler
dc.date.accessioned2021-06-23T19:19:57Z
dc.date.available2021-06-23T19:19:57Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAbstract Background: In this study, the authors attempted to determine if there was any effect of tube filling order on both routine (prothrombin time [PT], activated partial thromboplastin time [APTT], and fibrinogen) and specific coagulation parameters (protein S, protein C, antithrombin III, factor V Leiden, plasminogen, and D-dimer). Methods: Fifty-seven consecutive patients having coagulation parameters within the reference range (mean age ±SD, 32.14±5.59 years) were included in the study. In drawing blood, the first 2 tubes were 3.2% citrated coagulation tubes. Routine and specific coagulation parameters were studied on both tubes, and the results were compared using a paired sample t-test. Results: The comparison of all parameters revealed statistically-insignificant results. The difference in the levels of protein C between the 2 tubes approached significance (P=0.053). Conclusion: This study has shown some evidence that tube filling order in healthy subjects does not play a significant role on routine and specific coagulation parameters.en_US
dc.identifier.doi10.1309/RQ00WJ60KQXAM9B0
dc.identifier.endpage558en_US
dc.identifier.issn0007-5027
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-36649038572en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage556en_US
dc.identifier.urihttps://doi.org/10.1309/RQ00WJ60KQXAM9B0
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6034
dc.identifier.volume38en_US
dc.identifier.wosWOS:000249047700012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSerin, Erdinç
dc.institutionauthorBuğdaycı, Güler
dc.language.isoenen_US
dc.publisherAmer Soc Clinical Pathologyen_US
dc.relation.ispartofLabmedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSpecific Coagulation
dc.titleEffect of tube filling order on specific coagulation parameters in healthy subjectsen_US
dc.typeArticleen_US

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