Red cell distribution width-to-platelet count ratio is a promising predictor of functional bowel disease

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dc.authorid0000-0003-4520-4085en_US
dc.authorid0000-0001-7306-5233en_US
dc.authorid000-0003-4201-9757en_US
dc.authorid0000-0003-2811-0052en_US
dc.authorid0000-0002-4162-5563en_US
dc.authorid0000-0003-3651-4858en_US
dc.authorid0000-0002-7706-1181en_US
dc.authorid0000-0002-3836-2125en_US
dc.contributor.authorKahveci, Gizem
dc.contributor.authorAktaş, Gülali
dc.contributor.authorTel, Burçin Meryem Atak
dc.contributor.authorBilgin, Satılmış
dc.contributor.authorKurtkulağı, Özge
dc.contributor.authorBalcı, Buse
dc.contributor.authorErtürk, Aslı
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.date.accessioned2023-11-23T06:29:28Z
dc.date.available2023-11-23T06:29:28Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground. Hemogram parameters are not only diagnostic tools in haematological diseases, but their role in inflamma-tory conditions is also important. One of these haematological markers is a derived index, the so-called red cell distribution width-to -platelet count ratio (RPR). The role of RPR has been well established in various inflammatory conditions. Objectives. In the present study, we aimed to observe the RPR levels of patients with functional bowel disease (FBD), which is also considered as an inflammatory process, and to compare this to the healthy population. Material and methods. Patients diagnosed with FBD according to Rome IV criteria were included as the study group. Healthy vol-unteers were enrolled as control subjects. Patients with any form of anaemia or haematological disorders or inflammatory diseases were excluded. Age, gender and hemogram parameters were obtained from institutional databases. The data of the study and control groups was compared. Results. 158 subjects were enrolled in the study; 87 in the FBD group and 71 in the control group. The RPR of the FBD and control groups were 7% (2%) and 5% (1%), respectively. The difference in RPR between the FBD and control groups was statistically significant (p = 0.008). A RPR value higher than 6% has a 70% sensitivity and 52% specificity in detecting FBD. There was a significant and positive correlation between RPR levels and the presence of FBD (r = 0.22, p = 0.007). Conclusions. We suggest that elevated RPR levels could yield potential diagnostic benefits in the diagnosis of FBD. However, prospec-tive studies with a larger population are needed to confirm our results.en_US
dc.identifier.citationKahveci, G., Aktas, G., ATAK TEL, B. M., Bilgin, S., Kurtkulagi, O., Balci, B., ... & DUMAN, T. T. (2022). Red cell distribution width-to-platelet count ratio is a promising predictor of functional bowel disease. Family Medicine & Primary Care Review, 24(2).en_US
dc.identifier.doi10.5114/fmpcr.2022.115873
dc.identifier.endpage129en_US
dc.identifier.issn1734-3402
dc.identifier.issn2449-8580
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85134577895en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage126en_US
dc.identifier.urihttp://dx.doi.org/10.5114/fmpcr.2022.115873
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11874
dc.identifier.volume24en_US
dc.identifier.wosWOS:000835179500005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorBalcı, Buse
dc.institutionauthorErtürk, Aslı
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofFamily Medicine and Primary Care Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectErythrocyte Indicesen_US
dc.subjectBlood Plateletsen_US
dc.subjectInflammationen_US
dc.subjectPrevalenceen_US
dc.subjectFibrosisen_US
dc.subjectVolumeen_US
dc.titleRed cell distribution width-to-platelet count ratio is a promising predictor of functional bowel diseaseen_US
dc.typeArticleen_US

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