Comparison of clinical diagnosis and microbiological test results in vaginal infections

dc.authorid0000-0002-2860-1794
dc.authorid0000-0001-8232-628X
dc.authorid0000-0002-0839-7490
dc.authorid0000-0003-2245-7979
dc.contributor.authorKaraca, Mehmet
dc.contributor.authorBayram, Ayşen
dc.contributor.authorKoçoğu, Mücahide Esra
dc.contributor.authorGöçmen, Ahmet
dc.contributor.authorEkşi, Fahriye
dc.date.accessioned2021-06-23T18:54:23Z
dc.date.available2021-06-23T18:54:23Z
dc.date.issued2005
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractLower genital tract infections continue to be a problem due to the fact that the clinical diagnosis is usually inadequate, and subsequent care is suboptimal. This study aimed at evaluating the accuracy of clinical diagnosis by comparing it with microbiologic test results, and to determine the causative agents of vaginal infections. Sixty-seven nonpregnant women (18-45 years of age) with the clinical diagnosis of lower genital tract infection were enrolled in the study. Patients were not included if they had a history of vaginal infection during the previous three-month period or intrauterine device. The clinical diagnosis was based on the combinations of symptoms, direct observation of wet mount, homogeneous discharge, vaginal pH > 4.5, and detection of the amine odor after exposure of vaginal secretions to 10% KOH. Vaginal samples were taken with two cotton swabs, one was used for pH determination, and the second was utilized for microbiological tests. Gram staining and cultures with Sabouraud agar and chocolate agar were performed for microbiological diagnosis, and the results were compared. The clinical diagnoses included 26 (38.8%) candidiasis, 18 (26.8%) bacterial vaginosis, three (4.5%) trichomoniasis, and 20 (29.9%) mixed vaginal infections. Of the 26 patients with clinical diagnoses of candidiasis, 12 (46.1%) revealed Candiada albicans, nine (34.6) patients revealed microorganisms other than Candida species, nd five (19.2%) patients had no growth. Five (27.8%) bacterial vaginosis patients revealed Gardnarella vaginalis and 12 patients (66.6%) did not grow any microorganism. The overall rate of accurate clinical diagnoses confirmed by microbiological test results was 43.2%. Seventeen (43.6) of the 39 microbiological test results correlated with clinical diagnosis, and no growth was observed in 28 (41.8%) cultures. We conclude that the clinical diagnosis of vaginal infection is inadequate and should be confirmed with microbiological testing if the resources are available.en_US
dc.identifier.endpage174en_US
dc.identifier.issn0390-6663
dc.identifier.issue3en_US
dc.identifier.pmid16433157en_US
dc.identifier.scopus2-s2.0-28044466887en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage172en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4403
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-28044466887&partnerID=40&md5=98fcaa57aff20b86af119c9aaa5be0a3
dc.identifier.volume32en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoçoğu, Mücahide Esra
dc.language.isoenen_US
dc.relation.ispartofClinical and Experimental Obstetrics and Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClinical diagnosisen_US
dc.subjectMicrobiological diagnosisen_US
dc.subjectVaginal infectionen_US
dc.titleComparison of clinical diagnosis and microbiological test results in vaginal infectionsen_US
dc.typeArticleen_US

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