Laparoscopic Nissen Fundoplication: analysis of 162 patients

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dc.authorid0000-0001-8987-0763
dc.authorid0000-0002-2722-2469
dc.authorid0000-0001-6966-9149
dc.contributor.authorSarı, Alpaslan
dc.contributor.authorGönüllü, Neşet Nuri
dc.contributor.authorTiryaki, Çağrı
dc.contributor.authorYazıcıoğlu, Murat Burç
dc.contributor.authorKarğı, Ertuğrul
dc.date.accessioned2021-06-23T19:44:00Z
dc.date.available2021-06-23T19:44:00Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractWe aimed to evaluate the frequency of the need for proton pump inhibitor treatment following laparoscopic Nissen fundoplication (LNF) for gastroesophageal reflux disease (GERD). A total of 162 patients with GERD were treated surgically with LNF from October 2006 to March 2010 in our surgery department. Diagnoses were made by using upper gastrointestinal system (GIS) endoscopy and 24-hour pH monitoring, and all the patients underwent routine LNF surgery. The patients were questioned regarding complaints and proton pump inhibitor (PPI) usage during the postoperative period, and 40 patients who had postoperative GIS symptoms were included. Upper GIS endoscopy with antral biopsy for Helicobacter pylori (HP) identification and multichannel intraluminal impedance pH (MII-pH) monitoring were applied, and all the data were evaluated. The median postoperative follow-up time was 1.84 +/- 0.850 (0.29-3.48) years. PPI treatment frequency was 37.5% (15 patients) in the 40 symptomatic patients, or 9.26% in all 162 patients who were operated on. The reason for PPI usage in 3 patients (7.5%) was regarded as recurrence. HP positivity was 67.5% in the symptomatic patients and 73.3% in the PPI treated group; 40% (6 patients) recovery was achieved in the HP (+) patients by using an HP eradication treatment protocol. The operated patients displayed statistically significant results in increased quality of life (P = 0.001) and lowered DeMeester scores (P = 0.000) during the postoperative period when compared with the preoperative period. LNF treatment for GERD prevents pathologic reflux in the long term and maintains symptomatic control, which leads to increased and better quality of life. PPI treatment alone during the postoperative period does not indicate "recurrence.'' One of the most important reasons for recurrence is antral gastritis secondary to HP infection; PPI usage diminishes remarkably with an HP eradication protocol. MII-pH monitoring is an effective method of determining recurrences due to reflux and their types in postoperative symptomatic patients.en_US
dc.identifier.doi10.9738/INTSURG-D-15-00217.1
dc.identifier.endpage103en_US
dc.identifier.issn0020-8868
dc.identifier.issue1-2en_US
dc.identifier.scopus2-s2.0-84994234817en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage98en_US
dc.identifier.urihttps://doi.org/10.9738/INTSURG-D-15-00217.1
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8897
dc.identifier.volume101en_US
dc.identifier.wosWOS:000402279300016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKarğı, Ertuğrul
dc.language.isoenen_US
dc.publisherInt College Of Surgeonsen_US
dc.relation.ispartofInternational Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLaparoscopic Nissen Fundoplicationen_US
dc.subjectPPI Treatmenten_US
dc.subjectMultichannel Intraluminal Impedanceen_US
dc.titleLaparoscopic Nissen Fundoplication: analysis of 162 patientsen_US
dc.typeArticleen_US

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